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Pseudotyped Viruses for Phlebovirus
2023Rift Valley fever virus (RVFV) is a member of the Phlebovirus genus, one of the 20 genera in the Phenuiviridae family. RVFV causes disease in animals and humans and is transmitted by sandflies or ticks. However, research into RVFV is limited by the requirement for biosafety level 3 (BSL-3) containment.
Jiajing, Wu +2 more
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Phlebovirus infections in Greece
Journal of Medical Virology, 2015Sandfly fever viruses are endemic in the Mediterranean region causing to humans asymptomatic or mild infections to severe neurological syndromes. In order to investigate the epidemiology of phlebovirus infections in Greece, samples from 499 patients with acute febrile illness (50.2% accompanied by neurological symptoms) were tested during 2010-2014 by ...
Anna Papa +2 more
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Development of pan-phlebovirus RT-PCR assay
Journal of Virological Methods, 2016This study reports the pan-phlebovirus assay capable of detecting both sandfly/mosquito- and tick-borne phleboviruses. Sensitivity and specificity of the assay was verified using a panel of arboviruses. The RT-PCR assay is simple and sensitive, and thus well suited for screening of field samples.
Alexander S, Klimentov +8 more
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[Cell biology of phlebovirus entry].
Virologie (Montrouge, France), 2021Phleboviruses constitute a large group of arthropod-borne viruses (arboviruses), mainly transmitted to their hosts by sandflies and ticks, occasionally by mosquitoes. These viruses have a worldwide distribution and many cause serious diseases - often fatal - in both domestic animals and humans.
Zina M, Uckeley +4 more
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The Genus Phlebovirus and its Vectors
Annual Review of Entomology, 1988Repartition geographique. Importance en sante publique, biologie des vecteurs, interaction virus vecteur.
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Viremia and Immune Response with Sequential Phlebovirus Infections
The American Journal of Tropical Medicine and Hygiene, 1987Four groups of hamsters were infected sequentially with various combinations of Arumowot, Chagres, and Gabek Forest viruses. Following each infection, the survival, level of viremia, and immune response of the animals were monitored. All of the agents produced viremia in the hamsters, regardless of the order of their administration.
R B, Tesh, S M, Duboise
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The Phlebovirus Ribonucleoprotein: An Overview
In negative strand RNA viruses, ribonucleoproteins, not naked RNA, constitute the template used by the large protein endowed with polymerase activity for replicating and transcribing the viral genome. Here we give an overview of the structures and functions of the ribonucleoprotein from phleboviruses.Ferron, François, Lescar, Julien
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