Results 1 to 10 of about 8,146 (217)

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families [PDF]

Journal of Virology, 2015
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença‐Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya K. Amarasinghe, Michael Diamond, Adrianus C. M. Boon   +12 more
core   +9 more sources

Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.

PLoS Neglected Tropical Diseases, 2019
BackgroundLeishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis.
Carolina Torturella Rath, Laila Castro Schnellrath, Clarissa R Damaso, Luciana Barros de Arruda, Pedro Fernando da Costa Vasconcelos, Claudia Gomes, Marcia Dalastra Laurenti, Teresa Cristina Calegari Silva, Áislan de Carvalho Vivarini, Nicolas Fasel, Renata Meirelles Santos Pereira, Ulisses Gazos Lopes   +11 more
doaj   +7 more sources

Production, quantification, and infection of Amazonian Phlebovirus (Bunyaviridae) [PDF]

BIO-PROTOCOL, 2021
Phlebotomine vectors, sand flies of the order Diptera, are known to transmit Leishmania parasites as well as RNA viruses (arboviruses) to humans. The arbovirus, Icoaraci Phlebovirus (BeAN 24262 - ICOV), used in this study was isolated from Nectomys rodents, a mammalian species that is the same natural sylvatic reservoir of Leishmania (Leishmania ...
Carolina Rath, Aislan Vivarini, Renata Pereira, Ulisses Lopes   +3 more
  +6 more sources

Infections by viruses of the families Bunyaviridae and Filoviridae

OIE Revue Scientifique Et Technique, 2000
H. Zeller, M. Bouloy
exaly   +4 more sources

Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon alfacon-1 [PDF]

Antiviral Research, 2008
Punta Toro virus (PTV) is a member of the Bunyaviridae family, genus Phlebovirus, related to the highly pathogenic Rift Valley fever virus (RVFV). It produces a disease in hamsters that models severe Rift Valley fever (RVF) in humans. The recent outbreak of RVF in Kenya stresses the need to identify prophylactic and therapeutic measures for preventing ...
Brian B. Gowen, Min‐Hui Wong, Kie‐Hoon Jung, Lawrence M. Blatt, Robert W. Sidwell   +4 more
openalex   +5 more sources

Immunoprophylaxis of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with recombinant Eimeria profilin-like antigen [PDF]

International Immunopharmacology, 2008
Recombinant Eimeria antigen (rEA) has been shown to have potent anticancer and antiviral activity in respective mouse disease models, presumably through robust immune stimulation that occurs via TLR11, a pattern recognition receptor that recognizes profilin-like proteins expressed on apicomplexan protozoans.
Brian B. Gowen, John W. Judge, Min‐Hui Wong, Kie-Hoon Jung, Charles F. Aylsworth, Peter C. Melby, Barnett Rosenberg, John D. Morrey   +7 more
openalex   +5 more sources

Mosquito Feeding-Induced Enhancement of Cache Valley Virus (Bunyaviridae) Infection in Mice [PDF]

Journal of Medical Entomology, 1998
Cache-Valley (CV) virus, an arthropod-borne bunyavirus, recently has emerged as a significant veterinary pathogen causing infertility and congenital malformations in North American ruminants. To investigate the role of vector feeding on CV infection, adult mice were injected subcutaneously with CV, CV and vector thorax extract (a source of vector ...
John F. Edwards, Stephen Higgs, Barry J. Beaty   +2 more
openalex   +3 more sources

Sociodemographic characteristics, clinical manifestations, and concurrent outcomes of Oropouche fever and dengue in Espírito Santo, Brazil [PDF]

Revista Panamericana de Salud Pública
Objective. To compare sociodemographic and clinical characteristics and the outcome severity between confirmed cases of Oropouche fever and dengue in the state of Espírito Santo, Brazil. Methods. A cross-sectional study used secondary data from the state
João Paulo Cola, Thiago Nascimento do Prado, Otavio T. Ranzani, Ana Paula Brioschi dos Santos, Brenda Silva Freire, Raphael Lubiana Zanotti, Adriana Endlich da Silva Dela Costa, Karina Bertazo Del Carro, Lesliane de Amorim Lacerda Coelho, Cintia Lepaus Thomas, Dijoce Prates Bezerra, Orlei Amaral Cardoso, Angelica Espinosa Miranda, Ethel Leonor Noia Maciel, Creuza Rachel Vicente   +14 more
doaj   +2 more sources

The Antiviral RNAi Response in Vector and Non-vector Cells against Orthobunyaviruses. [PDF]

PLoS Neglected Tropical Diseases, 2017
BackgroundVector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and Piwi-
Isabelle Dietrich, Xiaohong Shi, Melanie McFarlane, Mick Watson, Anne-Lie Blomström, Jessica K Skelton, Alain Kohl, Richard M Elliott, Esther Schnettler   +8 more
doaj   +7 more sources

ASSOCIATION BETWEEN MOVEMENT AND SIN NOMBRE VIRUS (BUNYAVIRIDAE: HANTAVIRUS) INFECTION IN NORTH AMERICAN DEERMICE (PEROMYSCUS MANICULATUS) IN COLORADO [PDF]

Journal of Wildlife Diseases, 2013
Capture data from long-term, mark-recapture studies were used to evaluate movements of North American deermice (Peromyscus maniculatus) on mark-recapture webs in Colorado with respect to Sin Nombre virus (SNV) infection status, age, sex, and trapping site.
Brian R. Amman, Arie Manangan, Timothy D. Flietstra, Charles H. Calisher, Darin S. Carroll, Kent D. Wagoner, James N. Mills   +6 more
openalex   +3 more sources