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Development of pan-phlebovirus RT-PCR assay
Journal of Virological Methods, 2016This study reports the pan-phlebovirus assay capable of detecting both sandfly/mosquito- and tick-borne phleboviruses. Sensitivity and specificity of the assay was verified using a panel of arboviruses. The RT-PCR assay is simple and sensitive, and thus well suited for screening of field samples.
Alexander S, Klimentov +8 more
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Viremia and Immune Response with Sequential Phlebovirus Infections
The American Journal of Tropical Medicine and Hygiene, 1987Four groups of hamsters were infected sequentially with various combinations of Arumowot, Chagres, and Gabek Forest viruses. Following each infection, the survival, level of viremia, and immune response of the animals were monitored. All of the agents produced viremia in the hamsters, regardless of the order of their administration.
R B, Tesh, S M, Duboise
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The Phlebovirus Ribonucleoprotein: An Overview
In negative strand RNA viruses, ribonucleoproteins, not naked RNA, constitute the template used by the large protein endowed with polymerase activity for replicating and transcribing the viral genome. Here we give an overview of the structures and functions of the ribonucleoprotein from phleboviruses.Ferron, François, Lescar, Julien
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[Recent advance in phlebovirus].
Bing du xue bao = Chinese journal of virology, 2013Genus Phlebovirus is single negative-strand RNA virus, and belongs to family bunyaviridae. Its genomes have three segments including L, M and S encoding RNA-dependent RNA polymerase, envelope glycoprotein and nucleoprotein respectively. Phlebovirus is arbovirus and can be disseminated by arthropod.
Guo-Yu, Niu, Mi-Fang, Liang
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A New Phlebovirus Associated with Severe Febrile Illness in Missouri
New England Journal of Medicine, 2012Two men from northwestern Missouri independently presented to a medical facility with fever, fatigue, diarrhea, thrombocytopenia, and leukopenia, and both had been bitten by ticks 5 to 7 days before the onset of illness. Ehrlichia chaffeensis was suspected as the causal agent but was not found on serologic analysis, polymerase-chain-reaction (PCR ...
Laura K, McMullan +11 more
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Cell biology of phlebovirus entry
2019Phleboviruses constitute a large group of arthropod-borne viruses (arboviruses), mainly transmitted to their hosts by sandflies and ticks, occasionally by mosquitoes. These viruses have a worldwide distribution and many cause serious diseases - often fatal - in both domestic animals and humans.
Uckeley, Zina M +4 more
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Phlebovirus infection in Greece: a case report.
Hippokratia, 2016Sandfly-transmitted phleboviruses cause to humans an asymptomatic or mild infection to severe meningitis or encephalitis. Phleovirus infections are common in the Mediterranean countries during the summertime when sandflies are active. It is estimated that several cases remain undiagnosed.In July 2013, a 45-year-old Greek male, was admitted to the ...
A, Papa +4 more
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[Molecular epidemiology of phlebovirus in four provinces in Morocco].
Bulletin de la Societe de pathologie exotique (1990), 2017Sandflies are vectors of protozoa, viruses, and bacteria. To investigate the transmission of phleboviruses, a total of 8753 sandflies were collected in four foci of leishmania. A total of 16 distinct species were morphologically identified. Nested-PCR and cell culture screening for phleboviruses, using an assay targeting the polymerase gene, showed ...
N, Es-Sette +3 more
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