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Rift Valley fever phlebovirus, a bunyavirus, is a mosquito-borne, segmented RNA virus that can cause severe disease in humans and ruminants. An essential step in RVFV life cycle is the packaging of viral RNA segments to produce infectious virus particles
Breanna Tercero+3 more
semanticscholar +1 more source
NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery [PDF]
Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and ...
Barry, Gerald+10 more
core +3 more sources
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71
Viral infections are one of the leading causes in human mortality and disease. Broad-spectrum antiviral drugs are a powerful weapon against new and re-emerging viruses.
Chengfeng Gao+8 more
semanticscholar +1 more source
Emergence of Toscana Virus in Europe
Toscana virus (TOSV) is an arthropodborne virus first identified in 1971 from the sandfly Phlebotomus perniciosus in central Italy. Many case reports in travelers and clinical research and epidemiologic studies conducted around the Mediterranean region ...
Rémi N. Charrel+7 more
doaj +1 more source
Rift Valley fever phlebovirus (RVFV) is an arthropod-borne virus that can cause severe disease in ruminants and humans. Epidemics occur mainly after heavy rainfall, which leads to a significant increase in the occurrence of RVFV transmitting mosquitoes ...
F. Stoek+4 more
semanticscholar +1 more source
Genetic Diversity of Toscana Virus
Distribution of Toscana virus (TOSV) is evolving with climate change, and pathogenicity may be higher in nonexposed populations outside areas of current prevalence (Mediterranean Basin). To characterize genetic diversity of TOSV, we determined the coding
Ximena Collao+10 more
doaj +1 more source
Toscana virus infection in Catalonia (Spain) [PDF]
Toscana virus (TOSV), an arthropod-borne phlebovirus, is an important agent of acute meningitis and meningoencephalitis in the Mediterranean area. The epidemiology of the infection in humans in Catalonia is at present unknown.
Aranda, Carles+10 more
core +1 more source
Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K.+4 more
core +2 more sources
Insights into the Evolutionary Origin of Mediterranean Sandfly Fever Viruses
Sandfly-transmitted phleboviruses (family Phenuiviridae, order Bunyavirales) are associated with febrile illness and infections of the nervous system in humans.
Marco Marklewitz+6 more
doaj +1 more source
Serological Evidence of Phleboviruses in Domestic Animals on the Pre-Apennine Hills (Northern Italy)
Phleboviruses are arboviruses transmitted by sand flies, mosquitoes and ticks. Some sand fly-borne phleboviruses cause illnesses in humans, such as the summer fevers caused by the Sicilian and Naples viruses or meningitis caused by the Toscana virus ...
Davide Lelli+9 more
doaj +1 more source