Results 131 to 140 of about 7,818 (149)

Ddi1p and Rad23p play a cooperative role as negative regulators in the PHO pathway in Saccharomyces cerevisiae

Biochemical and Biophysical Research Communications, 2008
In Saccharomyces cerevisiae, the PHO pathway regulates expression of phosphate-responsive genes such as PHO5, which encodes repressible acid phosphatase (rAPase). In this pathway, Pho81p functions as an inhibitor of the cyclin-cyclin-dependent kinase (CDK) complex Pho80p-Pho85p.
Choowong Auesukaree, Yoshinobu Kaneko, Satoshi Harashima   +2 more
exaly   +3 more sources

Hyper‐invasive mutants define a novel Pho‐regulated invasion pathway in Escherichia coli

Molecular Microbiology, 1993
SummaryWe have isolated two transposon insertion mutations of the pst–phoU operon which result in the constitutive expression of the phoA gene product, alkaline phosphatase. The two mutations also render Escherichia coli invasive towards cultured HEp‐2 cells and define a novel Pho‐regulated invasion pathway.
A P, Sinai, P M, Bavoil
openaire   +2 more sources

Rpl12p affects the transcription of the PHO pathway high‐affinity inorganic phosphate transporters and repressible phosphatases

Yeast, 2011
AbstractThe ribosomal protein Rpl12p of Saccharomyces cerevisiae is encoded by duplicated genes, RPL12A and RPL12B. The gene products possess an identical amino acid sequence. Yeast strain 6EA1, which lacks both genes, is viable but exhibits a very slow‐growth phenotype. In this study, 6EA1 cells were transformed with plasmids carrying either RPL12A or
Wen-Yo, Tu, Yu-Chen, Huang, Li-Fan, Liu, Li-Hsueh, Chang, Ming F, Tam   +4 more
openaire   +2 more sources

Pho regulon promoter-mediated transcription of the key pathway gene aroG Fbr improves the performance of an l-phenylalanine-producing Escherichia coli strain

Applied Microbiology and Biotechnology, 2010
DAHP synthase (EC 4.1.2.15) is one of the key enzymes involved in aromatic amino acid biosynthesis in Escherichia coli. An approximately twofold decrease in DAHP synthase activity level was detected in the late growth phase of the L-phenylalanine (Phe)-producing E.
Vera G, Doroshenko, Irina S, Tsyrenzhapova, Alexander A, Krylov, Evgeniya M, Kiseleva, Vladimir Yu, Ermishev, Svetlana M, Kazakova, Irina V, Biryukova, Sergey V, Mashko   +7 more
openaire   +2 more sources

Stochastic π-Calculus Modelling of Multisite Phosphorylation Based Signaling: The PHO Pathway in Saccharomyces Cerevisiae

2008
We propose a stochastic π-calculus modelling approach able to handle the complexity of post-translational signalling and to overcome some limitations of the ordinary differential equations based methods. The model we developed is customizable without a priori assumptions to every multisite phosphorylation regulation.
Segata, Nicola, Blanzieri, Enrico
openaire   +1 more source

Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways

Biochemical Journal, 2012
In Saccharomyces cerevisiae, the Pho84 phosphate transporter acts as the main provider of phosphate to the cell using a proton symport mechanism, but also mediates rapid activation of the PKA (protein kinase A) pathway. These two features led to recognition of Pho84 as a transceptor.
Dieter R, Samyn, Lorena, Ruiz-Pávon, Michael R, Andersson, Yulia, Popova, Johan M, Thevelein, Bengt L, Persson   +5 more
openaire   +2 more sources

Air-Stable Pd(R-allyl)LCl (L= Q-Phos, P(t-Bu)₃, etc.) Systems for C–C/N Couplings: Insight into the Structure–Activity Relationship and Catalyst Activation Pathway

The Journal of Organic Chemistry, 2011
A series of Pd(R-allyl)LCl complexes [R = H, 1-Me, 1-Ph, 1-gem-Me(2), 2-Me; L = Q-Phos, P(t-Bu)(3), P(t-Bu)(2)(p-NMe(2)C(6)H(4)), P(t-Bu)(2)Np] have been synthesized and evaluated in the Buchwald-Hartwig aminations in detail, in addition to the preliminary studies on Suzuki coupling and α-arylation reactions.
Carin C C, Johansson Seechurn, Sébastien L, Parisel, Thomas J, Colacot   +2 more
openaire   +2 more sources

Are the Multiple Signal Transduction Pathways of the Pho Regulon Due to Cross Talk or Cross Regulation?

1996
The phosphate (Pho) regulon includes a large number of coregulated genes whose expression is controlled by the environmental (extracellular) inorganic phosphate (Pi) level. Altogether 11 Pho regulon promoters for a total of 38 different genes have now been characterized in E. coli or closely related bacteria (Fig. 15.1).
Barry L. Wanner, Weihong Jiang, Soo-Ki Kim, Sayaka Yamagata, Andreas Haldimann, Larry L. Daniels   +5 more
openaire   +1 more source

Sensing Inorganic Phosphate Starvation by the Phosphate-Responsive (PHO) Signaling Pathway of Saccharomyces cerevisiae

2013
Inorganic phosphate \((P_i)\) is an essential nutrient whose intracellular levels are maintained by the PHO pathway in Saccharomyces cerevisiae. \(P_i\) limitation triggers upregulation of the PHO genes whose gene products primarily function to counterbalance the \(P_i\) deficiency. Despite a growing catalogue of genes that are involved in signaling of
openaire   +1 more source

Distinct requirements for Pho, Sfmbt, and Ino80 for cell survival in Drosophila

Genetics, 2021
Katja Finkl, Jürg Müller, Müller Jürg   +2 more
exaly