Results 31 to 40 of about 1,127,547 (305)
A general biochemical kinetics data fitting algorithm for quasi-steady-state detection
Lietuvos Matematikos Rinkinys, 2016 We develop a general algorithm for fitting the biochemical kinetics data. The developed algorithm searches and analyzes numerous minima. This approach allows us to analyze biochemical data without a priori quasi-steady-state assumptions.
Justinas V. Daugmaudis +3 more
doaj +1 more source
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. [PDF]
, 2019 PGAM5 is a mitochondrial protein phosphatase whose genetic ablation in mice results in mitochondria-related disorders, including neurodegeneration. Functions of PGAM5 include regulation of mitophagy, cell death, metabolism and aging.
Agnew, Christopher +9 more
core +3 more sources
Hyperglycemia triggers HIPK2 protein degradation [PDF]
, 2016 Homeodomain interacting protein kinase-2 (HIPK2) is an evolutionary conserved kinase that modulates several key molecular pathways to restrain tumor growth and induce p53-depending apoptotic cell-death in response to anticancer therapies. HIPK2 silencing
Baldari, Silvia +6 more
core +2 more sources
Plant, Soil and Environment, 2014 Transgenic CrylAc and CpTI insect-resistant cotton SGK321 is widely adopted for many years in several regions of China, however the understanding of its potential effects on soil enzyme activities is not studied.
Y.J. Zhang +4 more
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Kinase and Phosphatase Engagement Is Dissociated Between Memory Formation and Extinction
Frontiers in Molecular Neuroscience, 2019 Associative long-term memories (LTMs) support long-lasting behavioral changes resulting from sensory experiences. Retrieval of a stable LTM by means of a large number of conditioned stimulus (CS) alone presentations produces inhibition of the original ...
Mario Rafael Pagani +2 more
doaj +1 more source
Cogent Food & Agriculture, 2023 Phosphorus (P) plays a tremendous and determinant role in plant growth. However, its availability is hampered by the presence of metallic ions in soils.
Regassa Ayana Bayisa
doaj +1 more source
Integration of a Phosphatase Cascade with the MAP Kinase Pathway provides for a Novel Signal Processing Function [PDF]
, 2009 We mathematically modeled the receptor-activated MAP kinase signaling by incorporating the regulation through cellular phosphatases. Activation induced the alignment of a phosphatase cascade in parallel with the MAP kinase pathway.
Alon +54 more
core +3 more sources
eLife, 2018 Allostery is an inherent feature of proteins, but it remains challenging to reveal the mechanisms by which allosteric signals propagate. A clearer understanding of this intrinsic circuitry would afford new opportunities to modulate protein function. Here,
Daniel A Keedy +9 more
doaj +1 more source
Phosphate solubilizing bacteria: Isolation of Bacteria and Phosphate Solubilizing Genes, Mechanism and Genetics of Phosphate Solubilization [PDF]
مجله بیوتکنولوژی کشاورزی, 2014 Phosphorus is one of the major plant nutrients that is least available in the soil. There are two components of P in soil, organic and inorganic phosphate.
Mohammad Reza Sarikhani +2 more
doaj +1 more source
Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs [PDF]
, 2016 DUSP5 is an inducible nuclear dual-specificity phosphatase that specifically interacts with and deactivates extracellular signal-regulated kinases ERK1 and ERK2, which are responsible for cell proliferation, differentiation, and survival. The phosphatase
Bongard, Robert D +6 more
core +3 more sources