Results 31 to 40 of about 91,637 (308)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Distribution of potentially toxic elements in the Brazilian phosphogypsum and phosphate fertilizers

E3S Web of Conferences, 2013
The Brazilian phosphate fertilizer is obtained by wet reaction of the igneous phosphate rock with concentrated sulphuric acid, giving as final product phosphoric acid and dehydrated calcium sulphate (phosphogypsum) as by-product.
Saueia C. H. R., Mazzilli B. P., Bourlegat F. M. Le, Costa G. J. L.   +3 more
doaj   +1 more source

EVALUATION OF ANTIFUNGAL ACTIVITY OF ANAEROBIC DIGESTATE AND ITS EFFECT ON GROWTH AND YIELD OF MAIZE [PDF]

, 2018
Pakistan is an agricultural country. The increased population leads to increasing demand for food. Unfortunately, crops are infected by different microbes and nutrient deficiency of soil adversely affects the yield of the crop ...
Badshah, Malik, Haq, Abdul, Khan, Alam, Zaffar, Nazia   +3 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Radionuclide distribution in soils of the Corumbataí River Basin, São Paulo State, Brazil [PDF]

Geochimica Brasiliensis, 2017
The use of phosphate fertilizers in sugar cane crops is a very common practice in Brazilian agriculture and, as a consequence, the 226Ra, 292Th and 40K activity concentration in soils may increase and become readily available for plants and transferred ...
Fabiano Tomazini da Conceição, Daniel Marcos Bonotto, Jairo Roberto Jiménez-Rueda, José A. Frutuoso Roveda   +3 more
doaj  

Challenges and opportunities on the use of bio fertilizers: examples from Senegal and Kenya [PDF]

, 2014
Not only phosphorus (P) bio available in soil is very low but phosphate fertilizing efficiency is also low. Consequently, annual world P demand increases predicting phosphorus stock end in the coming 125 years.
Dalpé, Y., Diop, M., Diouf, M., Faye, Aliou, Jefwa, J., Lesueur, Didier, Ndoye, I., Ndung'u-Magiroi, Keziah Wairimu   +7 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Characterization of phoA, a Bacterial Alkaline Phosphatase for Phi Use Efficiency in Rice Plant

Frontiers in Plant Science, 2019
Fertilizers and herbicides are two major components in the agriculture system for achieving crop productivity. Massive use of orthophosphate fertilizers and herbicides poses threats to phosphate reserves and aids the evolution of herbicide tolerant weed ...
Babu Ram, Babu Ram, Dhirendra Fartyal, Dhirendra Fartyal, Vijay Sheri, Panditi Varakumar, Bhabesh Borphukan, Donald James, Renu Yadav, Arun Bhatt, Pawan K. Agrawal, V. Mohan M. Achary, Malireddy K. Reddy   +12 more
doaj   +1 more source

Challenges and opportunities on the use of bio fertilizers: cases study from Senegal and Kenya [PDF]

, 2014
Not only phosphorus (P) bioavailable in soil is very low but phosphate fertilizing efficiency is also low. Consequently, annual world P demand increases predicting phosphorus stock end in the coming 125 years.
Dalpé, Y., Diop, Ma, Dioufa, M., Faye, Aliou, Jefwac, J., Lesueur, Didier, Ndoyee, I., Ndung'u-Magiroi, Keziah Wairimu   +7 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source