Scientific Reports, 2021 In the current study, APOB (rs1052031) genotype-guided proteomic analysis was performed in a cohort of Pakistani population. A total of 700 study subjects, including Coronary Artery Disease (CAD) patients (n = 480) and healthy individuals (n = 220) as a ...
Muneeza Zafar +10 more
doaj +1 more source
Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites [PDF]
, 2014 Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and production of essential lipid-derived molecules.
Gross, Steven P. +2 more
core +1 more source
Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion [PDF]
, 2018 Bio-based production of fatty acids and fatty acid-derived products can enable sustainable substitution of petroleum-derived fuels and chemicals. However, developing new microbial cell factories for producing high levels of fatty acids requires extensive
Ferreira, Raphael +3 more
core +1 more source
Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]
, 2014 published_or_final_versio
Fan, P, Li, M, Wang, Y
core +1 more source
Interplay between phospholipids and digalactosyldiacylglycerol in phosphate limited oats [PDF]
, 2009 Phosphate is an essential nutrient. In most soils it is limiting, which has resulted in that phosphate is supplied as fertilizer to increase crop yield.
Tjellström, Henrik
core +1 more source
Lipids under stress - a lipidomic approach for the study of mood disorders [PDF]
, 2015 The emerging field of lipidomics has identified lipids as key players in disease physiology. Their physicochemical diversity allows precise control of cell structure and signaling events through modulation of membrane prop- erties and trafficking of ...
Antonny +114 more
core +1 more source
Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]
, 2019 Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna +6 more
core +2 more sources
Lipid Droplet Biogenesis and Functions in Health and Disease [PDF]
, 2023 Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being recognized for their versatility beyond energy storage. Advances uncovering the intricacies of their biogenesis and the diversity of their physiological and ...
Du, Ximing +2 more
core +1 more source
Lipid droplet-organelle interactions: emerging roles in lipid metabolism. [PDF]
, 2015 Cellular homeostasis depends on the precisely coordinated use of lipids as fuels for energy production, building blocks for membrane biogenesis or chemical signals for intra-cellular and inter-cellular communication.
Barbosa, Antonio Daniel +2 more
core +2 more sources
Therapeutic approaches to drug targets in atherosclerosis [PDF]
, 2014 Non-communicable diseases such as cancer, atherosclerosis and diabetes are responsible for major social and health burden as millions of people are dying every year. Out of which, atherosclerosis is the leading cause of deaths worldwide.
Barde, Sonal R. +5 more
core +1 more source