Mitochondria‐Associated Endoplasmic Reticulum Membranes in Human Health and Diseases
MedComm, Volume 6, Issue 7, July 2025.MAM dysfunction is considered as an initiator or contributor in the progression of various diseases such as nervous system diseases, circulatory system diseases, digestive system diseases, locomotor system diseases, reproductive system diseases, endocrine system diseases, urinary system diseases, respiratory system diseases and cancer.
Yong Liu +10 more
wiley +1 more source
Metabolism and Translocation of Aminophospholipids in Mammalian Cells [PDF]
, 2012 In this study we investigated the metabolism, i.e. remodeling and translocation, of the aminophospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE). A new method for introduction of exogenous PS and PE molecular species to cultured cells
Kainu, Ville
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Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase [PDF]
, 2009 Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
ABDALLA, Dulcinéia Saes Parra +2 more
core +4 more sources
Endoplasmic Reticulum Stress in Cancer
MedComm, Volume 6, Issue 7, July 2025.Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou +5 more
wiley +1 more source
Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum
, 2018 Background The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only mature gametocytes will survive in the mosquito’s midgut.
Brown, Simon H J +5 more
core +1 more source
Identification and characterization of an efficient acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) gene from the microalga Chlorella ellipsoidea [PDF]
RT-PCR detection of DGAT1 genes in transgenic yeast (INVSc1). The yeast actin was used as an internal control. 1, The yeast transformed with pYES2.0; 2â5, the yeast expressing AtDGAT1, GmDGAT1, BnDGAT1 and CeDGAT1, respectively.
Chengming Fan +6 more
core +3 more sources
Fatty acid modulation of the endocannabinoid system and the effect on food intake and metabolism [PDF]
, 2013 Endocannabinoids and their G-protein coupled receptors (GPCR) are a current research focus in the area of obesity due to the system’s role in food intake and glucose and lipid metabolism.
Hryciw, Deanne H +3 more
core +3 more sources
Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry [PDF]
, 2015 The phospholipid (PL) requirement in fish is revealed by enhanced performance when larvae are provided PL-enriched diets. To elucidate the molecular mechanism underlying PL requirement in Atlantic salmon, Salmo salar, were fed a minimal PL diet and ...
Carmona-Antoñanzas, Greta +3 more
core +1 more source
Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis [PDF]
, 2008 Four homologous isoforms of glycerol-3-phosphate acyltransferase (GPAT), each the product of a separate gene, catalyze the synthesis of lysophosphatidic acid from glycerol-3-phosphate and long-chain acyl-CoA.
Coleman, Rosalind +2 more
core +2 more sources
Metabolism of polyunsaturated fatty acids in human bone marrow derived mesenchymal stromal cells [PDF]
, 2017 The application of human bone marrow derived mesenchymal stromal cells (hBMSCs) for regenerative or immunomodulatory therapies, e.g. treatment of the graft-versus-host disease, requires in vitro expansion of the cells.
Tigistu-Sahle, Feven
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