Results 61 to 70 of about 4,841 (163)

Comprehensive Genetic Map of Muscle Lipidome Reveals Novel Insights Into Flavor Variation in Ruminant Meat

open access: yesAdvanced Science, Volume 12, Issue 40, October 27, 2025.
Ruminant meat is widely appreciated for its distinctive flavor. Lipids play a central role in influencing meat flavor, yet their genetic and biochemical basis remains largely unexplored. Here, a comprehensive lipid genetic map of sheep muscle is constructed and 20 candidate genes potentially modulating lipid levels are identified to provide a roadmap ...
Xueying Zhang   +17 more
wiley   +1 more source

Fatty acid modulation of the endocannabinoid system and the effect on food intake and metabolism [PDF]

open access: yes, 2013
Endocannabinoids and their G-protein coupled receptors (GPCR) are a current research focus in the area of obesity due to the system’s role in food intake and glucose and lipid metabolism.
Hryciw, Deanne H   +3 more
core   +3 more sources

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

open access: yesMedComm, Volume 6, Issue 10, October 2025.
As pivotal regulators in diverse physiological and pathological processes, mitochondria‐associated endoplasmic reticulum membranes (MAMs) are critically involved in both health and diseases, including cancers, neurodegenerative disorders, metabolic diseases, cardiovascular diseases.
Hangnan Hong   +3 more
wiley   +1 more source

The genetics of lipid storage and human lipodystrophies. [PDF]

open access: yes, 2015
Life depends on securing sufficient energy intake to enable growth, movement, and reproduction. Throughout evolution, lifeforms have struggled to ensure adequate energy intake, and this remains a major challenge for many species.
Robbins, Ann L, Savage, David B
core   +2 more sources

Revisiting Cholesterol‐Lowering Nutraceuticals and Functional Foods: Mechanistic Insights Into Cholesterol Homeostasis and Gut Microbiota

open access: yesFood Chemistry International, Volume 1, Issue 3, Page 265-293, September 2025.
Mechanistic Insights into Cholesterol Homeostasis and Gut Microbiota. ABSTRACT The gut microbiota acts as a crucial intermediary between diets and human health. The accumulating evidence suggests that gut microbiota may play a significant role in cholesterol metabolism.
Xiaoxuan Zhang   +4 more
wiley   +1 more source

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

open access: yesGlia, Volume 73, Issue 9, Page 1841-1859, September 2025.
Main Points Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated ...
Marie L. Mather   +4 more
wiley   +1 more source

Reconstruction of the lipid metabolism for the microalga Monoraphidium neglectum from its genome sequence reveals characteristics suitable for biofuel production [PDF]

open access: yes, 2013
Bogen C, Al-Dilaimi A, Albersmeier A, et al. Reconstruction of the lipid metabolism for the microalga Monoraphidium neglectum from its genome sequence reveals characteristics suitable for biofuel production. BMC Genomics.
Alexander Goesmann   +12 more
core   +2 more sources

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, Volume 2, Issue 3, September 2025.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Identification and characterization of an efficient acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) gene from the microalga Chlorella ellipsoidea [PDF]

open access: yes
RT-PCR detection of DGAT1 genes in transgenic yeast (INVSc1). The yeast actin was used as an internal control. 1, The yeast transformed with pYES2.0; 2–5, the yeast expressing AtDGAT1, GmDGAT1, BnDGAT1 and CeDGAT1, respectively.
Chengming Fan   +6 more
core   +3 more sources

Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum

open access: yes, 2018
Background The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only mature gametocytes will survive in the mosquito’s midgut.
Brown, Simon H J   +5 more
core   +1 more source

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