Mass Spectrometry Reviews, EarlyView.Abstract Recently, ion mobility spectrometry‐mass spectrometry (IMS‐MS) has become more readily incorporated into various omics‐based workflows. These growing applications are due to developments in instrumentation within the last decade that have enabled higher‐resolution ion mobility separations.
Cameron N. Naylor, Gabe Nagy
wiley +1 more source
Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2
Movement Disorders, EarlyView.Abstract Background Bridge‐like lipid transfer proteins (BLTPs) mediate bulk lipid transport at membrane contact sites. Mutations in BLTPs are linked to both early‐onset neurodevelopmental and later‐onset neurodegenerative diseases, including movement disorders.
Sarah D. Neuman +4 more
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Phosphatidylcholine biosynthesis and choline transport in the anaerobic protozoon Entodinium caudatum [PDF]
, 1976 Fyfe L. Bygrave, R. M. C. Dawson
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Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy
Movement Disorders, EarlyView.Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik +8 more
wiley +1 more source
Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light
Medicinal Research Reviews, EarlyView.ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva +5 more
wiley +1 more source
Acetylcholinesterase Inhibition and Antioxidant Activity of DHA‐Disubstituted Phospholipids
Molecular Nutrition &Food Research, EarlyView.1,2‐Di‐DHA‐PC phospholipids in nutraceutical form may cross the blood‐brain barrier and inhibit acetylcholinesterase (AChE) activity, with an efficacy similar to galantamine. This suggests their potential as neuroprotective agents in the treatment of Alzheimer's disease.
Ernestina Garcia‐Quinto +4 more
wiley +1 more source
Phosphatidylcholine–cholesterol acyltransferase in the ultracentrifugal residual protein fraction of rat plasma [PDF]
, 1971 Michihiro Sugano
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Automated Data Processing Workflows for Non‐Expert Users of NMR Facilities
Magnetic Resonance in Chemistry, EarlyView.Modern NMR spectrometers are typically organized in centralized, ultrahigh‐field facilities with multiple instruments that benefit from shared infrastructure and expertise. The acquisition of NMR experiments goes hand in hand with the analysis of the resulting data.
Armin Afrough +2 more
wiley +1 more source
Simplex-structured matrix factorisation: application of soft clustering to metabolomic data. [PDF]
Sci RepLiu W, Murphy TB, Brennan L.
europepmc +1 more source
Association of Phosphatidylcholine with Soybean 7S Globulin and Its Effect on The Protein Conformation [PDF]
, 1979 Masaru Ohtsuru +3 more
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