Results 281 to 290 of about 33,361 (336)

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

Photochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman, Anju Meda, Kaitlyn A. Moore, Payal Srivastava, Anika Dasgupta, Andaleeb Sajid, Suresh V. Ambudkar, Huang‐Chiao Huang   +7 more
wiley   +1 more source

Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism. [PDF]

Ann Neurol
Guo K, Savelieff MG, Jang DG, Teener SJ, Zhao L, Hur J, Goutman SA, Feldman EL.   +7 more
europepmc   +1 more source

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo

Veterinary Dermatology, EarlyView.
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka, Elisabeta Samuel (Badulescu), Manolis K. Chatzis, Manolis N. Saridomichelakis   +3 more
wiley   +1 more source

A green dichromophoric protein enabling foliage mimicry in arthropods. [PDF]

Proc Natl Acad Sci U S A
Egorkin NA, Aleksin AM, Sedlov IA, Zhiganov NI, Bodunova DV, Varfolomeeva LA, Slonimskiy YB, Ziganshin RH, Popov VO, Boyko KM, Vassilevski AA, Maksimov EG, Sluchanko NN.   +12 more
europepmc   +1 more source

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

Experimental Physiology, EarlyView.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox, Aaron Raman, Timothy Fairchild, John P. Beilby, Bu B. Yeap, Jeremy K. Nicholson, Julien Wist, Jeremiah Peiffer, Nathan G. Lawler   +8 more
wiley   +1 more source

UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia. [PDF]

Front Mol Biosci
Xu Y, Zhu Y, Chen Q, Zhang X, Fang J, Xu W, Zhang X.   +6 more
europepmc   +1 more source

Mapping a reproducible water fraction and T1 using MP2RAGE and variable flip angle quantitative MRI protocols

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 1002-1016, February 2026.
Abstract Purpose Water fraction (WF) estimation, a form of quantitative MRI mapping, is typically performed using the variable flip angle (VFA) approach. In this study, WF estimation was extended to include the magnetization prepared with 2 rapid gradient echoes (MP2RAGE) protocol.
Eden Mama, Rona Shaharabani, José P. Marques, Aviv A. Mezer   +3 more
wiley   +1 more source

Metabolomics Analysis Uncovers Distinct Profiles of Liver Post-Transplant Patients by Immunosuppression Regimen. [PDF]

Metabolites
Baciu C, Hasjim BJ, Maleki S, Pasini E, Patel MK, Shojaee M, Azhie A, Saracino G, Asrani SK, Bhat M.   +9 more
europepmc   +1 more source

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 1, Page 26-40, January 2026.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Stocking density modulates tilapia (Oreochromis niloticus) performance and fillet quality through phospholipid remodeling. [PDF]

Sci Rep
Roldi G, Robath S, Porto C, Pilau E, Giaquinto P, Neto JF, Lala B, Mari GC, Santos CT, Anastácio GN, Cangianelli GH, Ferreira AL, Ouros CC, Chavesk GHC, Souza MLR, de Oliveira Marques D, Claudino-Silva SC.   +16 more
europepmc   +1 more source