Results 271 to 280 of about 35,571 (360)

Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay

Journal of Applied Toxicology, Volume 46, Issue 2, Page 652-668, February 2026.
ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt, Manuela Mayer, Andreas Schepky, Corie Ellison   +3 more
wiley   +1 more source

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride-Glucose Index. [PDF]

Metabolites
Naja K, Anwardeen N, Albagha O, Elrayess MA.   +3 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Cannabinoid Receptors CB1 and CB2 Activation Restores Hippocampal Lipid Profiles and Alleviates Autism-Like Behaviors in Valproic Acid-Induced ASD Rats. [PDF]

CNS Neurosci Ther
Wang H, Zhang M, Yang S, Jiang Y, Wu L, Sun C.   +5 more
europepmc   +1 more source

Comparative analysis of sex-dependent serum metabolomic patterns across the lifespan of rhesus macaques. [PDF]

Front Genet
Metzler LAP, Goy RW, Metzger JM, Emborg ME, Kapoor A.   +4 more
europepmc   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source

Blood Plasma Lipid Alterations Differentiating Psychotic and Affective Disorder Patients. [PDF]

Biomolecules
Golubova A, Stekolshchikova E, Gareeva A, Akhmerova I, Timerbulatov I, Zakurazhnaya V, Riabinina D, Reznik A, Morozova A, Andreyuk D, Kostyuk G, Petrova D, Serkina A, Khaitovich P, Tkachev A.   +14 more
europepmc   +1 more source

Phosphatidylethanolamine Improves Postnatal Growth Retardation by Regulating Mucus Secretion of Intestinal Goblet Cells in Piglets [PDF]

Nan Wang, Chengming Wang, Ming Qi, Xingtong Lin, Andong Zha, Bie Tan, Yulong Yin, Jing Wang   +7 more
openalex   +1 more source

Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian, Jingwen Deng, Yuzhu Hong, Ruitong Liu, Shengnan Li, Xiaoxiao He   +5 more
wiley   +1 more source

UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia. [PDF]

Front Mol Biosci
Xu Y, Zhu Y, Chen Q, Zhang X, Fang J, Xu W, Zhang X.   +6 more
europepmc   +1 more source