Results 51 to 60 of about 31,010 (310)
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
Advanced Functional Materials, EarlyView.MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling +4 more
wiley +1 more source
Phosphatidylethanolamine dynamics are required for osteoclast fusion [PDF]
Scientific Reports, 2017 AbstractOsteoclasts, responsible for bone resorption, are multinucleated cells formed by cell-cell fusion of mononuclear pre-osteoclasts. Although osteoclast fusion is a pivotal step for osteoclastogenesis, little is known about the mechanism involved.
Atsushi Irie +6 more
openaire +3 more sources
Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte
Advanced Materials Interfaces, EarlyView.This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao +7 more
wiley +1 more source
Journal of Biological Chemistry, 2011 Peroxidation of plasma lipoproteins has been implicated in the endothelial cell activation and monocyte adhesion that initiate atherosclerosis, but the exact mechanisms underlying this activation remain unclear.
Lilu Guo +6 more
semanticscholar +1 more source
Synthetic Phosphatidylethanolamines as Renin Inhibitors
Experimental Biology and Medicine, 1977 SummaryAnti-renin and hypotensive effects of synthetic PEs were examined.(i) Eighteen PEs including optical isomers were newly synthesized. Arachidonic acid, linolenic acid, and stearic acid were substituted at the positions of β, γ, or both. Natural PE was extracted from porcine kidney, and the lyso form was prepared by treatment of phospholipase A ...
Mizuo Miyazaki, Kenjiro Yamamoto
openaire +3 more sources
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
Advanced Science, EarlyView.This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang +16 more
wiley +1 more source
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Signal Transduction and Targeted Therapy, 2022 Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease characterized by injury to cardiomyocytes leading to various forms of cell death.
Xiao-Hui Ma +10 more
doaj +1 more source