Results 101 to 110 of about 9,975 (285)

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer [PDF]

, 2016
Apoptosis is an evolutionarily conserved and tightly regulated cell death modality. It serves important roles in physiology by sculpting complex tissues during embryogenesis and by removing effete cells that have reached advanced age or whose genomes ...
Barcinski, M, Birge, RB, Boeltz, S, Brekken, RA, Calianese, D, Carlson, J, Empig, C, Freimark, B, Herrmann, M, Huang, X, Hutchins, JT, Kumar, S, Mercer, J, Schett, G, Schroit, AJ, Wanderley, J   +15 more
core   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Serum metabolic profiling of oocyst-induced Toxoplasma gondii acute and chronic infections in mice using mass-spectrometry [PDF]

, 2018
Toxoplasma gondii is an obligate intracellular parasite causing severe diseases in immunocompromised individuals and congenitally infected neonates, such as toxoplasmosis encephalitis and toxoplasmic chorioretinitis. This study aimed to determine whether
Chen, Xiao-Qing, Cong, Wei, Elsheikha, Hany M., He, Shen-Yi, Zhou, Chun-Xue, Zhu, Xing-Quan   +5 more
core   +2 more sources

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Bleaching Of Fatty Acids With Obtained Adsorbents [PDF]

, 2021
This article presents the results of the adsorptive purification of fatty acids from dyes by the obtained clay adsorbents. It was determined that phospholipids, which are classified as nonionic surfactants, exhibit the highest sorption activity.
D.A., Azimova, D.S., Sagdullaeva, D.S., Salihanova, D.T., Ruzmetova, I.D., Eshmetov, M.A., Ismoilova, M.A., Mamajonova   +6 more
core   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

EM23, a natural sesquiterpene lactone from Elephantopus mollis H.B.K., induces apoptosis in human myeloid leukemia cells through thioredoxin- and reactive oxygen species-mediated signaling pathways

Frontiers in Pharmacology, 2016
Elephantopus mollis H.B.K. (EM) is a traditional herbal medicine with multiple pharmacological activities. However, the efficacy of EM in treating human leukemia is currently unknown.
Hongyu eLi, Manmei eLi, Guocai eWang, Fangyuan eShao, Wenbo eChen, Chao eXia, Sheng eWang, Yaolan eLi, Guangxiong eZhou, Zhong eLiu   +9 more
doaj   +1 more source

Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography. [PDF]

, 2015
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and ...
Bennett, Martin R, Bird, Joseph LE, Brindle, Kevin M, Davenport, Anthony P, Dweck, Marc R, Gallagher, Ferdia A, Irkle, Agnese, Joshi, Francis R, Lewis, David Y, Newby, David E, Rudd, James H, Skepper, Jeremy N, Vesey, Alex T, Warburton, Elizabeth A   +13 more
core   +5 more sources

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Concentration of Phosphatidylserine Influence Rates of Insulin Aggregation and Toxicity of Amyloid Aggregates In Vitro

, 2023
Mikhail Matveyenka, Kiryl Zhaliazka, Dmitry Kurouski   +2 more
openalex   +1 more source