Results 81 to 90 of about 466 (146)

Angiotensin II Alters Mitochondrial Membrane Potential and Lipid Metabolism in Rat Colonic Epithelial Cells

open access: yesBiomolecules
An over-active renin-angiotensin system (RAS) is characterized by elevated angiotensin II (Ang II). While Ang II can promote metabolic and mitochondrial dysfunction in tissues, little is known about its role in the gastrointestinal system (GI).
Darby D. Toth   +11 more
doaj   +1 more source

A Japanese Case of Lenz‐Majewski Syndrome With a Novel PTDSS1 Variant

open access: yesMolecular Genetics & Genomic Medicine
Background Lenz‐Majewski syndrome (LMS) is a rare genetic disorder characterized by osteosclerosis, intellectual disability, characteristic facies, and distinct craniofacial, dental, cutaneous, and distal‐limb anomalies.
Yasuko Kobari   +8 more
doaj   +1 more source

Lipidome Disturbances of Vibrio alginolyticus Associated with Citral Exposure

open access: yesMicroorganisms
Vibrio alginolyticus is an important antibiotic-resistant pathogen in aquaculture that can cause mortality in a wide range of aquatic animals and infect humans. It is urgently necessary to discover and develop effective antibiotic alternatives. Citral, a
Yanni Zhao   +7 more
doaj   +1 more source

Role of charged lipids in membrane structures — Insight given by simulations

open access: yes, 2016
Lipids and proteins are the main components of cell membranes. It is becoming increasingly clear that lipids, in addition to providing an environment for proteins to work in, are in many cases also able to modulate the structure and function of those ...
Vattulainen, Ilpo, Pöyry, Sanja
core   +1 more source

Dual fragmentation via collision-induced and oxygen attachment dissociations using water and its radicals for C=C position-resolved lipidomics

open access: yesCommunications Chemistry
Oxygen attachment dissociation (OAD) is a tandem mass spectrometry (MS/MS) technique for annotating the positions of double bonds (C=C) in complex lipids.
Hiroaki Takeda   +7 more
doaj   +1 more source

Multi-Omic Characterization of Epithelial–Mesenchymal Transition: Lipidomic and Metabolomic Profiles as Key Markers of TGF-β-Induced Transition in Huh7 Hepatocellular Carcinoma

open access: yesCells
Epithelial–mesenchymal transition (EMT) is a key process in cancer progression and fibrogenesis. In this study, EMT was induced in Huh7 hepatocellular carcinoma cells via TGF-β1 treatment, and the resulting lipidomic and metabolomic alterations were ...
Agnese Bertoldi   +7 more
doaj   +1 more source

Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release.

open access: yes, 2003
International audienceLigation of CD47 by its natural ligand thrombospondin (TSP), or cross-linking by CD47 antibodies, triggers caspase-independent cell death in normal and leukemic cells.
Rubio, Manuel   +9 more
core   +1 more source

Correlation of Anti‐Phosphatidylserine/Prothrombin and Anti‐Phosphatidylserine Antibodies with Pregnancy Outcomes

open access: yesAmerican Journal of Reproductive Immunology
ABSTRACTBackgroundThe objective of this study was to investigate the clinical relevance of anti‐prothrombin antibodies (aPT) and anti‐phosphatidylserine/prothrombin antibodies (aPS/PT) in relation to pregnancy outcomes and coagulation parameters, as well as immune markers.MethodsWe retrospectively analyzed 477 pregnant women with experienced at least ...
Junmiao Xiang   +3 more
openaire   +2 more sources

Variations in the milk lipidomic profile of lactating dairy cows fed the diets containing alfalfa hay versus alfalfa silage

open access: yesAnimal Nutrition
Alfalfa is primarily stored as silage or hay in livestock production. Previous research has shown that the storage method of grass significantly influences milk composition.
Kaizhen Liu   +12 more
doaj   +1 more source

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