Results 81 to 90 of about 31,210 (332)

Near-IR Absorbing BODIPY Derivates as Glutathione-Activated Photosensitizers for Selective Photodynamic Action [PDF]

, 2014
Cataloged from PDF version of article.Enhanced spatiotemporal selectivity in photonic sensitization of dissolved molecular oxygen is an important target for improving the potential and the practical applications of photodynamic therapy.
Atilgan, Awuah, Barranco, Cakmak, Chen, Choi, Cui, Dai, Dolmans, Dougherty, Dougherty, Erbas, Gallagher, Gołab, Guo, He, Hirschberg, Isik, Jesionek, Ji, Jiang, Jung, Kamkaew, Kou, Li, Li, Maeda, Mathews, Mcdonnell, Ormond, Ozlem, Pang, Raab, Rockson, Shao, Shibata, Stacey, Ulrich, von Tappeiner, Waksman, Wang, Yeh, Yogo, Yogo, You, Yu, Zhang, Zhang, Zheng, Zheng, Ålander   +50 more
core   +1 more source

The Rules of Human T Cell Fate in vivo. [PDF]

, 2020
The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells in vitro ...
Asquith, B, Beverley, P, Costa Del Amo, P, Debebe, B, Macallan, D, Nakaoka, S, Razavi-Mohseni, M, Wallace, D, Worth, A   +8 more
core   +1 more source

Phosphatidylserine Supplementation as a Novel Strategy for Reducing Myocardial Infarct Size and Preventing Adverse Left Ventricular Remodeling

International Journal of Molecular Sciences, 2021
Phosphatidylserines are known to sustain skeletal muscle activity during intense activity or hypoxic conditions, as well as preserve neurocognitive function in older patients.
David Schumacher, Adelina Curaj, M. Staudt, Franziska Cordes, A. Dumitraşcu, B. Rolles, C. Beckers, Josefin Soppert, Mihaela Rusu, S. Simsekyilmaz, K. Kneizeh, C. Ramachandra, D. Hausenloy, E. Liehn   +13 more
semanticscholar   +1 more source

Characterization of Phosphatidylserine Transport to the Locus of Phosphatidylserine Decarboxylase 2 in Permeabilized Yeast [PDF]

Journal of Biological Chemistry, 2001
In yeast, nascent phosphatidylserine (PtdSer) can be transported to the mitochondria and Golgi/vacuole for decarboxylation to synthesize phosphatidylethanolamine (PtdEtn). In strains with a psd1Delta allele for the mitochondrial PtdSer decarboxylase, the conversion of nascent PtdSer to PtdEtn can serve as an indicator of lipid transport to the locus of
W I, Wu, D R, Voelker
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics

Frontiers in Pharmacology, 2022
This study aimed to investigate the effects and underlying mechanisms of tormentic acid (TA) on carbon tetrachloride (CCl4)-induced liver fibrosis in rats.
Xing Lin, Yuanyuan Wei, Yan Li, Yuhua Xiong, Bin Fang, Cuiyu Li, Quanfang Huang, Renbin Huang, Jinbin Wei   +8 more
doaj   +1 more source

Transport of Phosphatidylserine from the Endoplasmic Reticulum to the Site of Phosphatidylserine Decarboxylase2 in Yeast [PDF]

Traffic, 2014
Over the past two decades, most of the genes specifying lipid synthesis and metabolism in yeast have been identified and characterized. Several of these biosynthetic genes and their encoded enzymes have provided valuable tools for the genetic and biochemical dissection of interorganelle lipid transport processes in yeast.
Muthukumar, Kannan, Wayne R, Riekhof, Dennis R, Voelker   +2 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Electrochemical regulation of budding yeast polarity.

PLoS Biology, 2014
Cells are naturally surrounded by organized electrical signals in the form of local ion fluxes, membrane potential, and electric fields (EFs) at their surface.
Armin Haupt, Alexis Campetelli, Daria Bonazzi, Matthieu Piel, Fred Chang, Nicolas Minc   +5 more
doaj   +1 more source

Comprehensive metabolomics of Philippine Stichopus cf. horrens reveals diverse classes of valuable small molecules for biomedical applications.

PLoS ONE, 2023
Stichopus cf. horrens is an economically important sea cucumber species in Southeast Asia due to their presumed nutritional and medicinal benefits. However, compared to other sea cucumbers such as Apostichopus japonicus, there are no biochemical studies ...
Vicenzo Paolo M Torreno, Ralph John Emerson J Molino, Hiyas A Junio, Eizadora T Yu   +3 more
doaj   +1 more source