Results 141 to 150 of about 16,748,637 (363)

Effects of prematuration culture with a phosphodiesterase-3 inhibitor on oocyte morphology and embryo quality in in vitro maturation. [PDF]

Clin Exp Reprod Med, 2021
Cheruveetil MA, Shetty PK, Rajendran A, Asif M, Rao KA.   +4 more
europepmc   +1 more source

The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]

, 2010
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
core   +1 more source

Periodontitis in patients with severe erectile dysfunction undergoing penile prosthesis implantation: Clinical and immunohistochemical study

Journal of Periodontology, EarlyView.
Abstract Background The relationship between periodontitis and erectile dysfunction (ED) has been poorly documented in Caucasian populations, particularly severe ED (SED) requiring penile prostheses. This study aimed to evaluate the association between periodontitis and SED in patients undergoing penile prosthesis implantation, and to identify clinical
Miguel Ángel Arrabal‐Polo, Ana López‐Toruño, Antonio Magan‐Fernández, Miguel Arrabal Martin, Natividad Martín‐Morales, Eva Rosel, Manuel Bravo, Francisco O´Valle, Francisco Mesa   +8 more
wiley   +1 more source

Epithelial Na+ Channel Stimulation by n-3 Fatty Acids Requires Proximity to a Membrane-bound A-kinase-anchoring Protein Complexed with Protein Kinase A and Phosphodiesterase [PDF]

, 2007
Frédérique Mies, Corentin Spriet, Laurent Héliot, Sarah Sariban-Sohraby   +3 more
openalex   +1 more source

Patient Characteristics, Disease Profile and Treatment Patterns in Mild and Moderate Psoriasis Patients: Results From Real‐World Clinical Practices in Five European Countries (PROSPECT Study)

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Categorisation of psoriasis (PsO) disease severity in patients varies, although body surface area (BSA) affected is commonly used (< 3% ‘mild’, 3%–10% ‘moderate’ and > 10% ‘severe’). While moderate‐severe PsO has been well‐studied, more limited information regarding mild‐to‐moderate PsO is available.
Emily Goddard, Aaron Keal, James Hetherington, Sophie Barlow, David Wu, Melany Worbes‐Cerezo, Alexander Litvintchouk   +6 more
wiley   +1 more source

Dual Activation of Phosphodiesterase 3 and 4 Regulates Basal Cardiac Pacemaker Function and Beyond. [PDF]

Int J Mol Sci, 2021
Vinogradova TM, Lakatta EG.
europepmc   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. [PDF]

, 2018
Numerous types of inhibitory neurons sculpt the performance of human neocortical circuits, with each type exhibiting a constellation of subcellular phenotypic features in support of its specialized functions.
Chang, Edward F, Cobbs, Charles, Lein, Ed, Madison, Daniel V, Micheva, Kristina D, Nana, Alissa L, Seeley, William W, Smith, Stephen J, Ting, Jonathan T, Weinberg, Richard J   +9 more
core   +1 more source

Inotropy and L‐type Ca²⁺current, activated by β₁‐ and β₂‐adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart [PDF]

, 2008
Torsten Christ, Alejandro Galindo‐Tovar, Marcus Thoms, Ursula Ravens, Alberto J. Kaumann   +4 more
openalex   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source