Results 161 to 170 of about 16,465,333 (371)

Effects of psoriatic arthritis‐targeted drugs on bone remodeling: Clinical evidence and molecular pathways

open access: yesRheumatology &Autoimmunity, EarlyView.
Mechanisms and therapeutic targets in psoriatic arthritis: balancing inflammatory bone resorption and bone formation. Abstract Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by diverse clinical manifestations. Of particular concern, osteopenia and osteoporosis are prevalent in 45.27% and 12.94% of PsA patients, respectively ...
Yingchao Sun   +3 more
wiley   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu   +6 more
wiley   +1 more source

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

open access: yes, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama   +4 more
core   +1 more source

The Prevalence and Severity of Pain in Patients With Systemic Sclerosis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT We investigated pain prevalence and severity in systemic sclerosis (SSc) and patient–physician perceptions. This was an internet‐based survey that compared perceptions of pain type, location, severity, associated factors between patients with SSc and physicians, and pain treatment prescription patterns in Japan in March 2023.
Sei‐ichiro Motegi   +6 more
wiley   +1 more source

Polygonatum sibiricum (Huang Jing) polysaccharide reduces diabetic cardiomyopathy through increasing cyclic guanosine monophosphate‐protein kinase G signaling in diabetic mice

open access: yesJournal of Diabetes Investigation
Aims/Introduction Diabetic cardiomyopathy (DCM) is a prevalent condition among individuals with diabetes, and is associated with a high mortality rate.
Shengping Lei   +5 more
doaj   +1 more source

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