Results 181 to 190 of about 16,465,333 (371)

Symptom Improvement Following Treatment with the Inhaled Dual Phosphodiesterase 3 and 4 Inhibitor Ensifentrine in Patients with Moderate to Severe COPD - A Detailed Analysis. [PDF]

Int J Chron Obstruct Pulmon Dis, 2020
Watz H, Rickard K, Rheault T, Bengtsson T, Singh D.   +4 more
europepmc   +1 more source

Hormonal Regulation of 3′,5′-Adenosine Monophosphate Phosphodiesterases in Cultured Rat Granulosa Cells* [PDF]

, 1984
Marco Conti, Barry G. Kasson, Aaron J.W. Hsueh   +2 more
openalex   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

Perspectives on Ensifentrine and Its Therapeutic Potential in the Treatment of COPD: Evidence to Date

International Journal of COPD
Muhammad Asad Faruqi,1 Malik M Khurram S Khan,1 David M Mannino1,2 1University of Kentucky College of Medicine, Lexington, KY, USA; 2COPD Foundation, Miami, FL, USACorrespondence: David M Mannino, Department of Medicine, University of Kentucky College of
Faruqi MA, Khan MMKS, Mannino DM
doaj  

Cilostazol, a Phosphodiesterase 3 Inhibitor, Moderately Attenuates Behaviors Depending on Sex in the Ts65Dn Mouse Model of Down Syndrome. [PDF]

Front Aging Neurosci, 2020
Tsuji M, Ohshima M, Yamamoto Y, Saito S, Hattori Y, Tanaka E, Taguchi A, Ihara M, Ogawa Y.   +8 more
europepmc   +1 more source

An Effect of Insulin on Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase Activity in Fat Cells

, 1973
Vincent C. Manganiello, Martha Vaughan
openalex   +1 more source

Myeloid cAMP Reduction Shifts Rhinovirus‐Induced Airway Inflammation From Neutrophilic to Eosinophilic by Suppressing M1‐Interstitial Macrophages

Allergy, EarlyView.
ABSTRACT Background Asthma exacerbations caused by human rhinovirus (hRV) infection are characterized by airway neutrophilia and reduced corticosteroid response, leading to significant healthcare costs and lung function impairment. The Gαs subunit of the trimeric G protein regulates immunopathological conditions by modulating cAMP levels.
Seong Ok Park, Erdenebileg Uyangaa, Hyo Jin Kim, Hee Won Byeon, Jin Young Choi, Koanhoi Kim, Jihyung Lee, Samuel Bertin, Eyal Raz, Seong Kug Eo   +9 more
wiley   +1 more source

Hesperetin-5,7,3'-O-Trimethylether Dually Inhibits Phosphodiesterase 3/4 and Methacholine-Induced Airway Hyperresponsiveness in Sensitized and Challenged Mice. [PDF]

Drug Des Devel Ther, 2020
Shih CH, Wang WH, Chen CM, Ko WC.
europepmc   +1 more source

Therapeutic potential of hesperidin in diabetes mellitus‐induced erectile dysfunction through Nrf2‐mediated ferroptosis and oxidative stress

Andrology, EarlyView.
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin, Wen Song, Jiaquan Mao, Peng Hu, Zhong Chen, Jihong Liu, Xiaodong Song, Qian Fang, Kai Cui   +8 more
wiley   +1 more source

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response. [PDF]

Oncotarget, 2020
Jabalee J, Towle R, Lawson J, Dickman C, Garnis C.   +4 more
europepmc   +1 more source