Studies on the Inhibition of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) by 2-(3,4-Dihydroxyphenyl)-7,8-dihydroxy-3-methoxychromen-4-one, a Flavonoid from Pistacia chinensis [PDF]
Chemistry, 2023 Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) regulates skeletal and soft tissue mineralization by hydrolyzing nucleotide triphosphates and cyclic nucleotides, and is involved in the modulation of immune system. In fact, ENPP1 degrades 2′,3′-
Abdur Rauf +7 more
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The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury
BMC Infectious Diseases, 2009 Background Acute kidney injury frequently accompanies sepsis. Endotoxin is known to reduce tissue levels of cAMP and low levels of cAMP have been associated with renal injury.
Seo Jeong Wook +5 more
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The role of cilostazol, a phosphodiesterase 3 inhibitor, on oocyte maturation and subsequent pregnancy in mice. [PDF]
PLoS ONE, 2012 It is important to identify effective contraceptive drugs that cause minimal disruption to physiological processes. Phosphodiesterase 3 (PDE3) inhibitors suppress meiosis in oocytes by decreasing the level of cAMP and blocking the extrusion of the first ...
Min Li +8 more
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PLoS ONE, 2014 Hepatocellular carcinoma (HCC) is the fifth common malignancy worldwide and the third leading cause of cancer-related death. Targeted therapies for HCC are being extensively developed with the limited success of sorafinib.
Liping Sun +5 more
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Inhaled Dual Phosphodiesterase 3/4 Inhibitors for the Treatment of Patients with COPD: A Short Review. [PDF]
Int J Chron Obstruct Pulmon Dis, 2021 Martin C, Burgel PR, Roche N.
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Adenosine 3′:5′‐monophosphate phosphodiesterase in chicken erythrocytes [PDF]
FEBS Letters, 1980 Erela Gorin, S. Dickbuch
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Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response. [PDF]
Oncotarget, 2020 Jabalee J +4 more
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Inhalation of the Phosphodiesterase-3 Inhibitor Milrinone Attenuates Pulmonary Hypertension in a Rat Model of Congestive Heart Failure [PDF]
Anesthesiology, 2007 Thomas Hentschel +8 more
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Anti-photoaging properties of the phosphodiesterase 3 inhibitor cilostazol in ultraviolet B-irradiated hairless mice. [PDF]
Sci Rep, 2016 Kim HN +4 more
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Identification of a Glycerophosphocholine Phosphodiesterase, GDE5, in chicken [PDF]
E3S Web of Conferences, 2021 Glycerophosphodiester phosphodiesterase (GDPD/GDE) catalyzes the hydrolysis of glycerophosphodiesters to glycerol 3-phosphate and alcohol. It was discovered that the glycerophosphodiesterase family plays a role in lipid metabolism and signal pathway in ...
Gao Hao, Chang Pingan
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