Results 191 to 200 of about 16,465,333 (371)

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

Andrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu, Kang Liu, Bo Wen, Peng Hu, Taotao Sun, Beining Li, Manan Sulaiman, Shujun Jiang, Tao Wang, Jihong Liu, Yang Luan   +10 more
wiley   +1 more source

Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats. [PDF]

Ann Transplant, 2020
Nakanuma S, Tajima H, Takamura H, Sakai S, Gabata R, Okazaki M, Shinbashi H, Ohbatake Y, Makino I, Hayashi H, Miyashita T, Fushida S, Ohta T.   +12 more
europepmc   +1 more source

Interrelationship Between Adenylate Cyclase Activity, Adenosine 3′:5′ Cyclic Monophosphate Phosphodiesterase Activity, Adenosine 3′:5′ Cyclic Monophosphate Levels, and Growth of Cells in Culture

, 1973
Wayne B. Anderson, Thomas Russell, Richard A. Carchman, Ira Pastan   +3 more
openalex   +1 more source

Inhibition of phosphodiesterase‐3 by levosimendan is sufficient to account for its inotropic effect in failing human heart

British Journal of Pharmacology, 2014
Ø. Ørstavik, Ø. Ørstavik, Atalgin Sh, Atalgin Sh, Jon Riise, Jon Riise, C. Dahl, C. Dahl, G. Andersen, G. Andersen, F. Levy, F. Levy, T. Skomedal, T. Skomedal, J. Osnes, J. Osnes, E. Qvigstad, E. Qvigstad   +17 more
semanticscholar   +1 more source

The effect of topical and intraurethral alprostadil on erectile function: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Erectile dysfunction (ED) affects up to 50% of men over 40. While phosphodiesterase‐5 inhibitors (PDE5i) are the first line of medical treatment, they are not always effective. Alprostadil, available in injectable, topical, and intraurethral forms, offers an alternative treatment modality.
Iason Papadopoulos, Maksim Tishukov, Ioannis Sokolakis, Ioannis Katafigiotis, Ioannis Leotsakos, Markos Karavitakis, Julian Marcon, Christian G Stief, Nikolaos Pyrgidis   +8 more
wiley   +1 more source

Substrate and effector specificity of a guanosine 3':5'-monophosphate phosphodiesterase from rat liver.

, 1977
Joel Moss, Vincent C. Manganiello, M Vaughan   +2 more
openalex   +1 more source

Phosphodiesterase 3 inhibitor cilostazol induces migraine-like attacks via cyclic AMP increase.

Brain : a journal of neurology, 2014
Song Guo, J. Olesen, M. Ashina
semanticscholar   +1 more source

Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends

Andrology, EarlyView.
Abstract Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retrospective analysis was conducted using the PearlDiver Mariner database (2010–2022).
Angelo Orsini, Eugenio Bologna, Gabriele Bignante, Francesco Lasorsa, Luca Lambertini, Arianna Biasatti, Giovanni Liguori, Michele Marchioni, Francesco Porpiglia, Giuseppe Lucarelli, Luigi Schips, Davide Arcaniolo, Marco De Sio, Edward E. Cherullo, Riccardo Autorino, Celeste Manfredi   +15 more
wiley   +1 more source

Penile vascular status in young men living with HIV experiencing erectile dysfunction: A comparative cross‐sectional pilot study

Andrology, EarlyView.
Abstract Background Erectile dysfunction in people living with HIV is a multifactorial disease, but the role of penile vascular status assessed by dynamic penile color Doppler echography is underexplored. Objectives This study assessed penile vascular status in young males living with HIV experiencing erectile dysfunction, comparing them to HIV ...
Giorgio Tiecco, Andrea Delbarba, Cosimo Colangelo, Marco Di Gregorio, Paolo Facondo, Matteo Riva, Carlo Cappelli, Emanuele Focà, Francesco Castelli, Eugenia Quiros‐Roldan   +9 more
wiley   +1 more source

Developmental regulation of unique adenosine 3',5'-monophosphate-specific phosphodiesterase variants during rat spermatogenesis. [PDF]

, 1996
Fabio Naro, Rui Zhang, Marco Conti
openalex   +1 more source