Results 191 to 200 of about 16,748,637 (363)

Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats. [PDF]

Ann Transplant, 2020
Nakanuma S, Tajima H, Takamura H, Sakai S, Gabata R, Okazaki M, Shinbashi H, Ohbatake Y, Makino I, Hayashi H, Miyashita T, Fushida S, Ohta T.   +12 more
europepmc   +1 more source

Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor [PDF]

, 2014
Arthur Kavanaugh, Philip J. Mease, Juan J. Gómez‐Reino, Adewale Adebajo, J. Wollenhaupt, Dafna D. Gladman, Éric Lespessailles, Stephen Hall, Marla Hochfeld, ChiaChi Hu, Douglas R. Hough, Randall M. Stevens, Georg Schett   +12 more
openalex   +1 more source

Inhibition of phosphodiesterase‐3 by levosimendan is sufficient to account for its inotropic effect in failing human heart

British Journal of Pharmacology, 2014
Ø. Ørstavik, Ø. Ørstavik, Atalgin Sh, Atalgin Sh, Jon Riise, Jon Riise, C. Dahl, C. Dahl, G. Andersen, G. Andersen, F. Levy, F. Levy, T. Skomedal, T. Skomedal, J. Osnes, J. Osnes, E. Qvigstad, E. Qvigstad   +17 more
semanticscholar   +1 more source

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

Brain Pathology, EarlyView.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik, Russell Pickford, Nicolas Dzamko, Kerry‐Anne Rye, Woojin Scott Kim   +4 more
wiley   +1 more source

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis

, 2005
Bo Ding, Jun‐ichi Abe, Wei Heng, Haodong Xu, Wenyi Che, Toru Aizawa, Weimin Liu, Carlos A. Molina, Junichi Sadoshima, Burns C. Blaxall, Bradford C. Berk, Yan Chen   +11 more
openalex   +2 more sources

Phosphodiesterase 3 inhibitor cilostazol induces migraine-like attacks via cyclic AMP increase.

Brain : a journal of neurology, 2014
Song Guo, J. Olesen, M. Ashina
semanticscholar   +1 more source

Cyclic 3',5'-Nucleotide Phosphodiesterase

Journal of Biological Chemistry, 1969
openaire   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Phosphodiesterase 3 A expression in gastrointestinal stromal tumors. [PDF]

Virchows Arch
Sihto H, Giger O, Toivanen K, Salmikangas S, Vesterinen T, Sampo M, Böhling T.   +6 more
europepmc   +1 more source

Supplementary Table 3 from Integrated Analysis of Transcriptomes of Cancer Cell Lines and Patient Samples Reveals STK11/LKB1–Driven Regulation of cAMP Phosphodiesterase-4D

, 2023
Ningning He, Nayoung Kim, Mee Song, Choa Park, Somin Kim, Eun Young Park, Hwa Young Yim, Kyunga Kim, Jong Hoon Park, Keun Il Kim, Fan Zhang, Gordon B. Mills, Sukjoon Yoon   +12 more
openalex   +1 more source