Management of erectile dysfunction with a novel orodispersible formulation of the PDE-5 inhibitor vardenafil [PDF]
, 2011 Erectile dysfunction (ED) is a medical condition which can affect men of all ages. As men live longer and the prevalence of cardiovascular disease and diabetes continue to increase, the problem of ED will become more prominent.
Cordina, Maria
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Drug, Healthcare and Patient Safety, 2015 Andrew L Dodgen,1 Kevin D Hill1,2 1Department of Pediatrics, Duke University Medical Center, 2Duke Clinical Research Institute, Durham, NC, USA Abstract: Sildenafil is a phosphodiesterase type-5 inhibitor approved for treatment of pulmonary arterial ...
Dodgen AL, Hill KD
doaj
Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients. [PDF]
Front Immunol, 2022 Leukes VN +9 more
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Prolonged priapism following single dose administration of sildenafil: A rare case report
Urology Annals, 2009 A case of priapism following the consumption of a single dose of sildenafil is reported. A 25-year-old unmarried healthy man consumed non-prescribed 50 mg sildenafil purchased over the counter.
Sharma Sachit +5 more
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Apremilast in the Treatment of Plaque Psoriasis: Differential Use in Psoriasis
Clinical, Cosmetic and Investigational Dermatology, 2022 Jia C Gao,1 Albert G Wu,1 Marissa N Contento,1 Jacqueline M Maher,1 Abigail Cline2 1School of Medicine, New York Medical College, Valhalla, NY, USA; 2Department of Dermatology, New York Medical College, New York, NY, USACorrespondence: Abigail Cline ...
Gao JC +4 more
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Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate. [PDF]
, 1982 In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm.
BURNSIDE, Beth +3 more
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Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle [PDF]
, 1987 Susan E. Bryson, Ian W. Rodger
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EFFECTS OF CYCLIC AMP‐ AND CYCLIC GMP‐PHOSPHODIESTERASE INHIBITORS ON IMMUNOLOGICAL RELEASE OF HISTAMINE AND ON LUNG CONTRACTION [PDF]
, 1981 Nelly Frossard +3 more
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Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro [PDF]
, 1994 Forssmann, W. G. +6 more
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Phosphodiesterase inhibitors and the cardiovascular system
Continuing Education in Anaesthesia Critical Care & Pain, 2007 Phosphodiesterase is a ubiquitous enzyme that catalyses the hydrolysis of phosphodiester bonds. It is responsible for the hydrolysis of cyclic 3,5 adenosine monophosphate (cAMP) and 3,5 cyclic guanosine monophosphate (cGMP). Both cAMP, and to a lesser extent cGMP, have an important role in the regulation of inotropic mechanisms in the human myocardium.
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