Results 1 to 10 of about 35,832 (220)

Chronic Sildenafil Improves Erectile Function and Endothelium-dependent Cavernosal Relaxations in Rats: Lack of Tachyphylaxis

European Urology, 2005
Diane Gorny, J Bernabe, Laurent Alexandre   +2 more
exaly  

Sildenafil

Reactions Weekly
openaire   +1 more source

Sildenafil

Reactions Weekly, 2016
openaire   +1 more source

Sildenafil

Reactions Weekly, 2015
openaire   +1 more source

Sildenafil

Reactions Weekly, 2005
openaire   +1 more source

Acute sildenafil administration decreases the susceptibility to induced atrial fibrillation in sheep [PDF]

Journal of Molecular and Cellular Cardiology Plus
Sildenafil has been shown to decrease ventricular arrhythmias. We investigated whether sildenafil could similarly decrease atrial fibrillation (AF) burden through direct effects on atrial electrophysiology.
George W.P. Madders, Nathan C. Denham, David C. Hutchings, Charlotte E.R. Smith, Alice S. Whitley, Mohammed Obeidat, Andrew W. Trafford, Charles M. Pearman, Katharine M. Dibb   +8 more
doaj   +2 more sources

Placental effects and transfer of sildenafil in healthy and preeclamptic conditionsResearch in context

EBioMedicine, 2019
Background: The phosphodiesterase-5 inhibitor (PDE5) sildenafil has emerged as a promising treatment for preeclampsia (PE). However, a sildenafil trial was recently halted due to lack of effect and increased neonatal morbidity.
Emilie Hitzerd, Michelle Broekhuizen, Katrina M. Mirabito Colafella, Marija Glisic, René de Vries, Birgit C.P. Koch, Michiel A. de Raaf, Daphne Merkus, Sam Schoenmakers, Irwin K.M. Reiss, A.H. Jan Danser, Sinno H.P. Simons   +11 more
doaj   +2 more sources

Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial [PDF]

The Journal of Headache and Pain
Background Cyclic guanosine monophosphate (cGMP)-mediated mechanisms plays a role in migraine pathophysiology. Sildenafil, a phosphodiesterase type 5 inhibitor, increases intracellular cGMP and can reliably induce migraine attacks in women.
Anas Mohammad, Ditte Bork Iversen, Nete Lundager Klokker Rausgaard, Christina Kruuse, Dagmar Beier, Tore Bjerregaard Stage, Lanfranco Pellesi   +6 more
doaj   +2 more sources

Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers

Drug Design, Development and Therapy, 2017
Milko Radicioni,1 Chiara Castiglioni,1 Andrea Giori,2 Irma Cupone,3 Valeria Frangione,4 Stefano Rovati4 1CROSS Research S.A., Phase I Unit, Arzo, Switzerland; 2IBSA Farmaceutici Italia, Lodi, Italy; 3Bouty S.p.A., Strada Padana Superiore, Cassina De ...
Radicioni M, Castiglioni C, Giori A, Cupone I, Frangione V, Rovati S   +5 more
doaj   +2 more sources

A real‐world pharmacovigilance study of FDA adverse event reporting system events for sildenafil

Andrology, 2023
Sildenafil, a selective inhibitor of phosphodiesterase type 5 (PDE5), is widely used for the treatment of erectile dysfunction (ED). However, the safety profile of sildenafil, including adverse event (AEs), requires comprehensive evaluation.
Y. Wang, Bin Zhao, Haiyan Yang, Zheng Wan   +3 more
semanticscholar   +1 more source