Results 1 to 10 of about 12,336 (293)

A reagent to access methyl sulfones [PDF]

Nature Communications
A chemical reagent to access methyl sulfones has been developed. Its reaction with various bis-nucleophiles leads to the rapid formation of previously unknown heteroaromatic methyl sulfones. Analogous strategy can also be used to construct alkyl-, CHF2-,
Yaroslav Poplavskyi, Vasyl Ripenko, Sergei Bova, Angelina Biitseva, Yurii V. Dmitriv, Andrei A. Tolmachev, Iryna V. Sadkova, Iryna Pishel, Oleksii Grygorov, Vo Quang Huy Phan, H. V. Rasika Dias, Pavel K. Mykhailiuk   +11 more
doaj   +3 more sources

Hydrogenation of β-Keto Sulfones to β-Hydroxy Sulfones with Alkyl Aluminum Compounds: Structure of Intermediate Hydroalumination Products

Molecules, 2022
β-Hydroxy sulfones are important in organic synthesis. The simplest method of β-hydroxy sulfones synthesis is the hydrogenation of β-keto sulfones. Herein, we report the reducing properties of alkyl aluminum compounds R3Al (R = Et, i-Bu, n-Bu, t-Bu and n-
Michał Kotecki, Zbigniew Ochal, Paweł Socha, Vadim Szejko, Łukasz Dobrzycki, Mariola Stypik, Wanda Ziemkowska   +6 more
doaj   +2 more sources

Two-Step Azidoalkenylation of Terminal Alkenes Using Iodomethyl Sulfones [PDF]

Molecules, 2019
The radical azidoalkylation of alkenes that was initially developed with α-iodoesters and α-iodoketones was extended to other activated iodomethyl derivatives.
Nicolas Millius, Guillaume Lapointe, Philippe Renaud   +2 more
doaj   +2 more sources

Rongalite addition to dienones: diastereoselectivity in cyclic sulfone synthesis; stereochemical rationalization and prospects as a general conjugate nucleophile [PDF]

Beilstein Journal of Organic Chemistry
A detailed experimental and computational study of the diastereoselectivity of cyclic sulfone synthesis by reaction of Rongalite with doubly electrophilic dienones is presented.
Melina Goga, Hao Zong, James Franco, Jazmine Prana, Rudolph Michel, Antonia Muro, Elana Rubin, Janet Brenya, Henk Eshuis, Magnus W. P. Bebbington   +9 more
doaj   +2 more sources

Rh-Catalyzed Asymmetric Hydrogenation of α-Substituted Alkenyl Sulfones: Highly Chemo- and Enantioselective Access to Chiral Sulfones

Organic Letters, 2023
Rh–(R,R)-f-spiroPhos complex-catalyzed asymmetric hydrogenation of α-substituted alkenyl sulfones has been achieved, affording the chiral γ-keto sulfones and simple α-alkyl-substituted sulfones in high yields (96–99%) with excellent chemo ...
Xiaoxue Wu, Guofu Zi, Guohua Hou
exaly   +2 more sources

Copper-catalyzed sulfonylation of alkenes with CH3SSO3Na [PDF]

BMC Chemistry
A successful methodology for the copper-catalyzed dehydrogenated methylsulfonylation of alkenes utilizing CH3SSO3Na in conjunction with hypervalent iodine reagents was successfully established. This method offers a practical avenue to obtain allyl methyl
Xiaoli Chen, Ge Wu
doaj   +2 more sources

Antimicrobial and Biofilm-Preventing Activity of l-Borneol Possessing 2(5H)-Furanone Derivative F131 against S. aureus—C. albicans Mixed Cultures

Pathogens, 2022
Candida albicans and Staphylococcus aureus are human pathogens that are able to form mixed biofilms on the surface of mucous membranes, implants and catheters.
Rand Sulaiman, Elena Trizna, Alena Kolesnikova, Alsu Khabibrakhmanova, Almira Kurbangalieva, Mikhail Bogachev, Airat Kayumov   +6 more
doaj   +1 more source

Chloroaluminate Ionic Liquid Immobilized on Magnetic Nanoparticles as a Heterogeneous Lewis Acidic Catalyst for the Friedel–Crafts Sulfonylation of Aromatic Compounds

Molecules, 2022
Chloroaluminate ionic liquid bound on magnetic nanoparticles (Fe3O4@O2Si[PrMIM]Cl·AlCl3) was prepared and used as a heterogenous Lewis acidic catalyst for the Friedel–Crafts sulfonylation of aromatic compounds with sulfonyl chlorides or p-toluenesulfonic
Ngoc-Lan Thi Nguyen, Quoc-Anh Nguyen, Tien Khoa Le, Thi Xuan Thi Luu, Kim-Ngan Thi Tran, Phuoc-Bao Pham   +5 more
doaj   +1 more source

A Study on the Chemistry and Biological Activity of 26-Sulfur Analogs of Diosgenin: Synthesis of 26-Thiodiosgenin S-Mono- and Dioxides, and Their Alkyl Derivatives

Molecules, 2022
A chemoselective procedure for MCPBA oxidation of 26-thiodiosgenin to corresponding sulfoxides and sulfone was elaborated. An unusual equilibration of sulfoxides in solution was observed.
Aneta M. Tomkiel, Dorota Czajkowska-Szczykowska, Ewa Olchowik-Grabarek, Lucie Rárová, Szymon Sękowski, Jacek W. Morzycki   +5 more
doaj   +1 more source

Easy Access To Allylic Sulfones Through Transition Metal-Free Hydrosulfonylation Of Allenes

, 2021
A Brønsted acid-mediated addition of (hetero)aryl and (cyclo)alkyl sodium sulfinates to N-allenyl derivatives is described under very smooth conditions. This reaction provided a practical and efficient protocol for the synthesis of allylic sulfones in an
Marc, Taillefer, Sebastien, Lemouzy, Lucas, Pages, Florian, Monnier   +3 more
core   +1 more source