Results 11 to 20 of about 28,609 (228)

Sildenafil

open access: yesReactions Weekly, 2017
Swimming-induced pulmonary edema (SIPE) occurs during swimming and scuba diving, usually in cold water, in susceptible healthy individuals, especially military recruits and triathletes.
JOHN J. FREIBERGER   +17 more
core   +4 more sources

Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers

open access: yesDrug Design, Development and Therapy, 2017
Milko Radicioni,1 Chiara Castiglioni,1 Andrea Giori,2 Irma Cupone,3 Valeria Frangione,4 Stefano Rovati4 1CROSS Research S.A., Phase I Unit, Arzo, Switzerland; 2IBSA Farmaceutici Italia, Lodi, Italy; 3Bouty S.p.A., Strada Padana Superiore, Cassina De ...
Radicioni M   +5 more
doaj   +1 more source

The issue of recreational use of sildenafil [PDF]

open access: yesJournal of Education, Health and Sport
Introduction and purpose Erectile dysfunction (ED) is defined as the inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse.
Krystian Wdowiak   +9 more
doaj   +4 more sources

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

open access: yesDrug Design, Development and Therapy, 2016
Mona Mohamed El-Naa,1 Mohamed Othman,2,3 Sheren Younes4,5 1Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6 October City, Egypt; 2Preparatory Year College, University of Hail, Hail, Kingdom of Saudi Arabia; 3Faculty of ...
El-Naa MM, Othman M, Younes S
doaj   +1 more source

Use of Sildenafil Citrate for the Treatment of Erectile Dysfunction in Stallions: First Case Reports. [PDF]

open access: yesReprod Domest Anim
ABSTRACT Pharmacological aids can be useful alternatives to enhance penile erection and/or improve ejaculatory function, thereby prolonging the reproductive life of stallions with ejaculatory disorders. This study aimed to evaluate the effects of sildenafil citrate in the treatment of erectile dysfunction and on semen quality in two aged stallions, a ...
Cavalero TMS   +8 more
europepmc   +2 more sources

Portopulmonary hypertension practice patterns after liver transplantation

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats

open access: yesCogent Medicine, 2018
Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability.
Somchai Sawatdee   +7 more
doaj   +1 more source

Central retinal vein and artery occlusion associated with sildenafil: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2023
Background Sildenafil is a selective phosphodiesterase type 5 inhibitor used for the treatment of erectile dysfunction and pulmonary hypertension. It is available over the counter in many countries. While there have been a few reports of retinal vascular
Ali Torkashvand   +3 more
doaj   +1 more source

Avoiding pitfalls when modelling ligands in macromolecular crystallography. [PDF]

open access: yesActa Crystallogr D Struct Biol
Flawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Smart OS   +4 more
europepmc   +2 more sources

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