Results 141 to 150 of about 97,473 (302)

Targeted Systemic Therapies for Atopic Dermatitis in Australia: A Narrative Review

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease estimated to affect approximately 30% of children and 10%–15% of adults in Australia. Of those with this condition, one in five is estimated to have moderate‐to‐severe disease.
Diana Rubel   +5 more
wiley   +1 more source

Clinical and Molecular Effect of the Anti–IL‐18 Antibody Aletekitug in Adults With Atopic Dermatitis

open access: yesAllergy, EarlyView.
At Week 12, aletekitug was associated with a −68.3% percentage change from baseline in EASI score. Aletekitug improved the transcriptional profile of lesional skin towards that of non‐lesional skin at Week 4 and Week 12. Aletekitug was well‐tolerated; no serious adverse event or death occurred, and no patient withdrew due to an adverse event.
Joanne Ellis   +32 more
wiley   +1 more source

Penile vascular status in young men living with HIV experiencing erectile dysfunction: A comparative cross‐sectional pilot study

open access: yesAndrology, EarlyView.
Abstract Background Erectile dysfunction in people living with HIV is a multifactorial disease, but the role of penile vascular status assessed by dynamic penile color Doppler echography is underexplored. Objectives This study assessed penile vascular status in young males living with HIV experiencing erectile dysfunction, comparing them to HIV ...
Giorgio Tiecco   +9 more
wiley   +1 more source

Low‐intensity shockwave therapy for erectile dysfunction due to diabetes mellitus or coronary artery disease: An individual participant data meta‐analysis from a single center

open access: yesAndrology, EarlyView.
Abstract Background Low‐intensity shockwave therapy (LiST) is a first‐line treatment for vasculogenic erectile dysfunction (ED). However, its efficacy in challenging cases, such as ED solely due to type 2 diabetes mellitus (DM) or coronary artery disease (CAD), has not been adequately assessed.
Nikolaos Pyrgidis   +3 more
wiley   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

open access: yesAndrology, EarlyView.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu   +18 more
wiley   +1 more source

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

open access: yesAndrology, EarlyView.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco   +6 more
wiley   +1 more source

Comparative efficacy of combination therapy including regenerative therapies versus monotherapy for erectile dysfunction: A systematic review and meta‐analysis

open access: yesAndrology, EarlyView.
Abstract Background and objective The Current European Association of Urology guidelines do not provide recommendation for combination of regenerative therapies with standard therapies for erectile dysfunction. The aim of this study was to compare the efficacy of combined regenerative therapy with monotherapy for erectile dysfunction.
Alberto Quistini   +12 more
wiley   +1 more source

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

open access: yesAndrology, EarlyView.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A   +7 more
wiley   +1 more source

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