Results 141 to 150 of about 2,974,682 (398)

Differential Effects of Phosphodiesterase-5 Inhibitors on Hypoxic Pulmonary Vasoconstriction and Pulmonary Artery Cytokine Expression [PDF]

, 2005
Ben M. Tsai, Mark W. Turrentine, Brett C. Sheridan, Meijing Wang, Andrew C. Fiore, John W. Brown, Daniel R. Meldrum   +6 more
openalex   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

iMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang, Lanmei Yin, Zhaobin Wang, Jun Li, Xianglin Zeng, Qiye Wang, Jianzhong Li, Kang Xu, Huansheng Yang, Yulong Yin   +9 more
wiley   +1 more source

Perspectives on Ensifentrine and Its Therapeutic Potential in the Treatment of COPD: Evidence to Date

International Journal of COPD
Muhammad Asad Faruqi,1 Malik M Khurram S Khan,1 David M Mannino1,2 1University of Kentucky College of Medicine, Lexington, KY, USA; 2COPD Foundation, Miami, FL, USACorrespondence: David M Mannino, Department of Medicine, University of Kentucky College of
Faruqi MA, Khan MMKS, Mannino DM
doaj  

Clinical deterioration after sildenafil cessation in patients with pulmonary hypertension

Vascular Health and Risk Management, 2008
Anne M Keogh, Andrew Jabbour, Christopher S Hayward, Peter S MacdonaldHeart Lung Transplant Unit, St Vincent’s Hospital, Sydney, New South Wales, AustraliaAbstract: Sildenafil is a selective inhibitor of phosphodiesterase type 5 (PDE-5).
Anne M Keogh, Andrew Jabbour, Christopher S Hayward, Peter S Macdonald   +3 more
doaj  

Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients. [PDF]

Front Immunol, 2022
Leukes VN, Malherbe ST, Hiemstra A, Kotze LA, Roos K, Keyser A, De Swardt D, Gutschmidt A, Walzl G, du Plessis N.   +9 more
europepmc   +1 more source

P1‐426: BENEFICIAL EFFECTS OF PHOSPHODIESTERASE 4 INHIBITORS ON HYPERTENSION‐INDUCED DEFECTS IN MEMORY FUNCTION IN RATS [PDF]

, 2014
Sugin Lal Jabaris S, Haridass Sumathy, M Sugumar, Raja Solomon, S. Humby Monica, Chidambaram Saravana Babu, Sadagopan Thanikachalam   +6 more
openalex   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection? [PDF]

, 2018
David Hutchings, Simon Anderson, Jessica L. Caldwell, Andrew W. Trafford   +3 more
openalex   +1 more source

Periodontitis in patients with severe erectile dysfunction undergoing penile prosthesis implantation: Clinical and immunohistochemical study

Journal of Periodontology, EarlyView.
Abstract Background The relationship between periodontitis and erectile dysfunction (ED) has been poorly documented in Caucasian populations, particularly severe ED (SED) requiring penile prostheses. This study aimed to evaluate the association between periodontitis and SED in patients undergoing penile prosthesis implantation, and to identify clinical
Miguel Ángel Arrabal‐Polo, Ana López‐Toruño, Antonio Magan‐Fernández, Miguel Arrabal Martin, Natividad Martín‐Morales, Eva Rosel, Manuel Bravo, Francisco O´Valle, Francisco Mesa   +8 more
wiley   +1 more source

Second messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab, Limulus polyphemus [PDF]

, 1989
The biochemical mechanisms by which octopamine, catecholamines and the peptide proctolin exert their actions on Limulus cardiac muscle were investigated.
Groome, J. R., Watson, Winsor H., III
core   +2 more sources