The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice. [PDF]
Barbieri D+10 more
europepmc +1 more source
Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. [PDF]
Richard H. Kessin+3 more
openalex +1 more source
Cardiac Uses of Phosphodiesterase-5 Inhibitors
Phosphodiesterase-5 inhibitors (PDE5Is) improve erectile function by enhancing nitric oxide availability in the penis and its supplying vasculature, resulting in vasodilation and increased blood flow. PDE5Is might benefit cardiovascular diseases because phosphodiesterase-5 is also located elsewhere in the body, including the pulmonary and systemic ...
Bryan G. Schwartz+5 more
openaire +3 more sources
Abstract Objectives Abdominal pain related disorders of gut–brain interaction (AP‐DGBIs) such as irritable bowel syndrome (IBS) and functional abdominal pain‐not otherwise specified (FAP) are common conditions in children, significantly impacting quality of life.
Jip Groen+17 more
wiley +1 more source
Analyzing the Clinical Efficacy of a Type 5 Phosphodiesterase Inhibitor Combined With Ziyin Baihuo Granules in the Treatment of Erectile Dysfunction. [PDF]
Wang R+6 more
europepmc +1 more source
Ixekizumab Type I Allergy in a Patient With Psoriasis
ABSTRACT A 52‐year‐old Caucasian woman was referred for an allergy workup of suspected type I allergy to the interleukin (IL)‐17A inhibitor ixekizumab. Five months after ixekizumab initiation, she suddenly developed intense pruritus and three small wheals at the injection site approximately 30 min after injection, lasting up to 3 days.
Carina Borst+2 more
wiley +1 more source
Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients. [PDF]
Leukes VN+9 more
europepmc +1 more source
Genital Psoriasis: Shining Light on This Hidden Disease
Psoriasis occurring on skin of the genital and perigenital regions has specific diagnostic and treatment requirements due to the sensitivity and private nature of these areas. A multidisciplinary group of experts in the management of genital psoriasis, the Genital Psoriasis Wellness Consortium, convened to discuss the impact of genital psoriasis on ...
Jennifer Cather+19 more
wiley +1 more source
Avanafil for treatment of erectile dysfunction: review of its potential
Ryan M Burke,1 Jeffery D Evans21The University of Louisiana at Monroe College of Pharmacy, Monroe, LA, 2The University of Louisiana at Monroe College of Pharmacy, Shreveport, LA, USAAbstract: Avanafil is a medication that was recently approved by the US ...
Burke RM, Evans JD
doaj
Apremilast in the Treatment of Plaque Psoriasis: Differential Use in Psoriasis
Jia C Gao,1 Albert G Wu,1 Marissa N Contento,1 Jacqueline M Maher,1 Abigail Cline2 1School of Medicine, New York Medical College, Valhalla, NY, USA; 2Department of Dermatology, New York Medical College, New York, NY, USACorrespondence: Abigail Cline ...
Gao JC+4 more
doaj