Results 171 to 180 of about 2,886,292 (384)
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari+45 more
wiley +1 more source
Role of phosphodiesterase in glucagon resistance of large adipocytes
The role of phosphodiesterase in glucagon resistance of large adipocytes was investigated. A comparison was made of phosphodiesterase activities of homogenates prepared from isolated small (mean diameter ≃ 45 μm) and large (mean diameter ≃ 78 μm ...
Richard A. De Santis+3 more
doaj
Phosphodiesterase inhibitors and the cardiovascular system
Phosphodiesterase is a ubiquitous enzyme that catalyses the hydrolysis of phosphodiester bonds. It is responsible for the hydrolysis of cyclic 3,5 adenosine monophosphate (cAMP) and 3,5 cyclic guanosine monophosphate (cGMP). Both cAMP, and to a lesser extent cGMP, have an important role in the regulation of inotropic mechanisms in the human myocardium.
openaire +2 more sources
ABSTRACT This open‐label, single‐arm, multicenter clinical study evaluated the treatment satisfaction, efficacy, and safety of 0.5% delgocitinib ointment twice daily for 12 weeks, applied to face/neck lesions caused by ≥ 3 months use of topical steroids or tacrolimus ointment in patients with atopic dermatitis (AD).
Masatoshi Abe+5 more
wiley +1 more source
Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle [PDF]
Susan E. Bryson, Ian W. Rodger
openalex +1 more source
The Prevalence and Severity of Pain in Patients With Systemic Sclerosis
ABSTRACT We investigated pain prevalence and severity in systemic sclerosis (SSc) and patient–physician perceptions. This was an internet‐based survey that compared perceptions of pain type, location, severity, associated factors between patients with SSc and physicians, and pain treatment prescription patterns in Japan in March 2023.
Sei‐ichiro Motegi+6 more
wiley +1 more source
A model protocol for the cryopreservation and recovery of motile lizard sperm using the phosphodiesterase inhibitor caffeine. [PDF]
Campbell L+6 more
europepmc +1 more source
Positive Effects of Caffeine Therapy in a Girl with PDE2A‐Related Paroxysmal Dyskinesia
Movement Disorders Clinical Practice, EarlyView.
Katerina Bernardi+2 more
wiley +1 more source