Results 191 to 200 of about 2,886,292 (384)

Inhibitors of cyclic nucleotide phosphodiesterases produced by streptomyces. IV. Inhibition of cyclic nucleotide phosphodiesterases by reticulol.

, 1977
Yoshio Furutani, TOMIO TAKEUCHI, HAMAO UMEZAWA   +2 more
openalex   +2 more sources

Phosphodiesterase Inhibitors for Pulmonary Hypertension [PDF]

New England Journal of Medicine, 2010
GALIE', NAZZARENO, Rubin LJ, Simonneau G.   +2 more
openaire   +2 more sources

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

Andrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu, Kang Liu, Bo Wen, Peng Hu, Taotao Sun, Beining Li, Manan Sulaiman, Shujun Jiang, Tao Wang, Jihong Liu, Yang Luan   +10 more
wiley   +1 more source

Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction

JACC: Basic to Translational Science, 2017
Summary: There has been considerable focus on the potential role of nitric oxide (NO) and phosphodiesterase (PDE)-5 inhibition in treating heart failure with preserved ejection fraction (HFpEF). However, the results from studies have been conflicting. In
Lucas Cruz, MD, John J. Ryan, MD
doaj  

The Contracting and Swallowing Activity of Arterial Endothelial Cells Visualized by Carbon Technique (Shimamoto 1973) and the Inhibitory Effect of Cyclic AMP Phosphodiesterase Inhibitors, EG467 and EG626

, 1974
Takio Shimamoto
openalex   +2 more sources

The effect of topical and intraurethral alprostadil on erectile function: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Erectile dysfunction (ED) affects up to 50% of men over 40. While phosphodiesterase‐5 inhibitors (PDE5i) are the first line of medical treatment, they are not always effective. Alprostadil, available in injectable, topical, and intraurethral forms, offers an alternative treatment modality.
Iason Papadopoulos, Maksim Tishukov, Ioannis Sokolakis, Ioannis Katafigiotis, Ioannis Leotsakos, Markos Karavitakis, Julian Marcon, Christian G Stief, Nikolaos Pyrgidis   +8 more
wiley   +1 more source

Iijima Y., F. Nakagawa, S. Handa, T. Oda, A. Naito and M. Yamazaki, Biological properties of griseolic acid, a cyclic AMP phosphodiesterase inhibitor with an adenine group (1985) FEBS Letters 192, 179‐183 [PDF]

, 1986

openalex   +1 more source

Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends

Andrology, EarlyView.
Abstract Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retrospective analysis was conducted using the PearlDiver Mariner database (2010–2022).
Angelo Orsini, Eugenio Bologna, Gabriele Bignante, Francesco Lasorsa, Luca Lambertini, Arianna Biasatti, Giovanni Liguori, Michele Marchioni, Francesco Porpiglia, Giuseppe Lucarelli, Luigi Schips, Davide Arcaniolo, Marco De Sio, Edward E. Cherullo, Riccardo Autorino, Celeste Manfredi   +15 more
wiley   +1 more source

Differential regulation of TNF‐α and IL‐1β production from endotoxin stimulated human monocytes by phosphodiesterase inhibitors [PDF]

, 1992
Katherine L. Molnar-Kimber, L. Yonno, Richard J. Heaslip, Barry M. Weichman   +3 more
openalex   +1 more source

Penile vascular status in young men living with HIV experiencing erectile dysfunction: A comparative cross‐sectional pilot study

Andrology, EarlyView.
Abstract Background Erectile dysfunction in people living with HIV is a multifactorial disease, but the role of penile vascular status assessed by dynamic penile color Doppler echography is underexplored. Objectives This study assessed penile vascular status in young males living with HIV experiencing erectile dysfunction, comparing them to HIV ...
Giorgio Tiecco, Andrea Delbarba, Cosimo Colangelo, Marco Di Gregorio, Paolo Facondo, Matteo Riva, Carlo Cappelli, Emanuele Focà, Francesco Castelli, Eugenia Quiros‐Roldan   +9 more
wiley   +1 more source