Results 261 to 270 of about 2,886,292 (384)

Phosphodiesterase‐5 Inhibitor Therapy for Left Ventricular Assist Device Patients: More Data, More Questions

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Gaurav Gulati, Michael S. Kiernan
doaj   +1 more source

Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment. [PDF]

open access: yesJ Card Fail, 2017
Nakano SJ   +9 more
europepmc   +1 more source

Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1995
C. Genain   +8 more
semanticscholar   +1 more source

Inspiratory Muscle Training on Exercise Capacity, Dyspnoea and Health Status in Pulmonary Hypertension: A Randomised Controlled Trial

open access: yesRespirology, EarlyView.
ABSTRACT Background and Objective To evaluate the effects of a high‐intensity inspiratory muscle training on respiratory muscle strength, exercise capacity, dyspnoea, and health‐related quality of life (HRQL) in patients with pulmonary hypertension (PH). Methods Single‐blinded, randomised controlled trial 35 women with clinically stable PH (subgroups 1
Fabrício Farias da Fontoura   +8 more
wiley   +1 more source

Impact of acute caffeine intake on local tolerance to cold before and after total sleep deprivation

open access: yesExperimental Physiology, EarlyView.
Abstract Total sleep deprivation (TSD) alters local cold tolerance and could thus increase the risk of cold injury. We evaluated the impact of acute caffeine intake, the main countermeasure to TSD‐related deleterious effects, on local cold tolerance before and after TSD.
Baptiste de Lorgeril   +11 more
wiley   +1 more source

Effects of soluble guanylyl cyclase stimulation on muscle oxygenation and exercise capacity in heart failure with mildly reduced ejection fraction

open access: yesExperimental Physiology, EarlyView.
Abstract Heart failure (HF) with a mildly reduced ejection fraction (HFmrEF; 40%–49%) is present in ≤25% of HF patients. Therapeutic treatment options for HFmrEF‐associated exercise intolerance are limited. Nitric oxide (NO)‐independent stimulation of soluble guanylyl cyclase to improve peripheral vasodilatation offers a novel approach to enhance ...
Ramona E. Weber   +10 more
wiley   +1 more source

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