Results 301 to 310 of about 2,974,682 (398)

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
wiley   +1 more source

Repositioning Triazoles as Phosphodiesterase-4 Inhibitors to Suppress COVID-19 Cytokine Storms and Fungal Co-Infections via Docking and Simulation. [PDF]

J Cell Mol Med
Almohaimeed HM, Chatterjee A, Alaqabawi MR, Alsulaimani F, Basri AM, Jafer A, Shater AF, Saleh FM, Dhara B, Uti DE, Alum EU.   +10 more
europepmc   +1 more source

Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang, Ruo‐Lan Shi, You‐Xia Huang, Li‐Ni Liu, Jia‐Sheng Tao, Xian‐Hui Li, Xiao‐Da Li   +6 more
wiley   +1 more source

Jascayd (nerandomilast): a novel PDE4B inhibitor for idiopathic pulmonary fibrosis. [PDF]

Ann Med Surg (Lond)
Hujjat SFZ, Chandani HK, Chandani DK, Khan MS, Mahmoud A.   +4 more
europepmc   +1 more source

Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics

Pest Management Science, Volume 82, Issue 2, Page 1668-1679, February 2026.
Microphenomics is a new technique for detecting the very early resistance of powdery mildew in wheat seedlings, after 24, 48, and 72 h from infection. A number of 29, 42, and 34 genes models were identified to harbor significant SNP markers associated with the early resistance to WPM.
Amira M.I. Mourad, Hanaa M.S. Ibrahim, Stefanie Lück, Andreas Börner, Dimitar Douchkov   +4 more
wiley   +1 more source

PDE Inhibitors and Autophagy Regulators Modulate CRE-Dependent Luciferase Activity in Neuronal Cells from the Mouse Suprachiasmatic Nucleus. [PDF]

Molecules
Maronde E, Rami A.
europepmc   +1 more source

Green synthesis of silver nanoparticles using fermentation extracts from a mangrove soil bacterium: morphological characterization, and antifungal activities against rice blast fungus

Pest Management Science, Volume 82, Issue 2, Page 2035-2047, February 2026.
This study synthesized silver nanoparticles (RFE‐AgNPs) with multifaceted inhibitory effects on Pyricularia oryzae using mangrove soil bacterial natural products and evaluated their toxicity effects on Artemia salina. Abstract BACKGROUND Rice blast, caused by Pyricularia oryzae, poses a formidable threat to global rice production.
Liwang Fei, Jianbing Liang, Shiquan Fu, Ying Xu, Lingyun Hao   +4 more
wiley   +1 more source

Apremilast in osteoarthritis: exploring its therapeutic mechanisms. [PDF]

Drugs Context
Rafiei F, Sadeghipour S, Hosseini Marvast SM, Mandegary A, Soltani H.   +4 more
europepmc   +1 more source

Pathogenesis of Vitiligo: Integrating Immune and Non‐Immune Cell Crosstalk

The Journal of Dermatology, Volume 53, Issue 2, Page 188-199, February 2026.
ABSTRACT Vitiligo is an acquired autoimmune disease characterized by depigmented macules resulting from melanocyte loss. It is a complex multifactorial disorder in which genetic predisposition is combined with environmental factors; however, its detailed etiology remains unclear.
Shintaro Inoue
wiley   +1 more source

Clinical and Molecular Effect of the Anti–IL‐18 Antibody Aletekitug in Adults With Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 539-551, February 2026.
At Week 12, aletekitug was associated with a −68.3% percentage change from baseline in EASI score. Aletekitug improved the transcriptional profile of lesional skin towards that of non‐lesional skin at Week 4 and Week 12. Aletekitug was well‐tolerated; no serious adverse event or death occurred, and no patient withdrew due to an adverse event.
Joanne Ellis, Léa Fortunato, Hannah Wajdner, Ester Del Duca, Joanna Barnard, Joanna C. Betts, Swaroop Bose, John Browning, Núria Buil‐Bruna, Scott Van Buren, Eden David, Scott Dinehart, Puneet Dhawan, Yeriel Estrada, Parima Ghafoori, Kiranmai Gumireddy, Zhenghong Li, Wei Jing Loo, Fiona Lovegrove, Jenny Lowe, Lawrence Charles Parish, Will Powley, Naveen Prasad, Joel Correa Da Rosa, Marieta Ruseva, Neda Shokrian, Farhat Syed, Chun‐Hang Tang, Gabriel K. Wong, John B. Kelly, Nicolas Wisniacki, Iain Uings, Emma Guttman‐Yassky   +32 more
wiley   +1 more source