Results 321 to 330 of about 2,974,682 (398)

The Molecular Mechanism of PDE1 Regulation. [PDF]

open access: yesCells
Nielsen J   +3 more
europepmc   +1 more source

Prescription Trends and the Role of Cardiologists in the Diagnosis and Treatment of Erectile Dysfunction. [PDF]

open access: yesJ Cardiovasc Dev Dis
Tkaczyk F   +5 more
europepmc   +1 more source

Phosphodiesterase inhibitors

Current Anaesthesia & Critical Care, 1993
Despite the justifiable concern about the use of oral cyclic adenosine monophosphate phosphodiesterase (cAMP PDE) inhibitors, the intravenous preparations are clearly effective in the treatment of acute heart failure, whether it occurs de novo or complicating chronic congestive heart failure (CHF), and in low output states following cardiac surgery ...
R, Andrews, A J, Cowley
  +6 more sources

Phosphodiesterase 4 inhibitors

Journal of the American Academy of Dermatology, 2018
Historically, drugs available for treating atopic dermatitis (AD) have been limited to topical corticosteroids and topical calcineurin inhibitors, with systemic immunosuppressants and phototherapy reserved for severe AD. Despite their efficacy and infrequent adverse events, phobia about the use of topical steroids and calcineurin inhibitors has limited
Rema, Zebda, Amy S, Paller
openaire   +2 more sources

Phosphodiesterase‐5 Inhibitor Therapy for Pulmonary Hypertension in the United States. Actual versus Recommended Use

Annals of the American Thoracic Society, 2018
Rationale: Care of patients with pulmonary hypertension is complex. Although pulmonary vasodilators are effective for Group 1 pulmonary hypertension, clinical guidelines and the Choosing Wisely Campaign recommend against routine use for Groups 2 and 3 ...
Deborah Kim   +8 more
semanticscholar   +1 more source

Phosphodiesterase-5 Inhibitors

2013
Nitric oxide (NO) signaling plays a key role in modulating vascular tone and remodeling in the pulmonary circulation. The guanylate cyclase/cyclic guanylate monophosphate-signaling pathway primarily mediates nitric oxide signaling. This pathway is critical in normal regulation of the pulmonary vasculature, and is an important target for therapy in ...
Barbara A, Cockrill, Aaron B, Waxman
openaire   +2 more sources

Phosphodiesterase inhibitors

2021
Cerebral ischemic diseases are among the most prevalent causes of death and the leading cause of adult disability worldwide. Although many studies have investigated the pathophysiological mechanisms involved in the cerebral ischemic injury, no effective pharmacological treatment has been established.
openaire   +1 more source

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