Results 121 to 130 of about 41,991 (249)

Direct Assay to Evaluate Phosphoenolpyruvate Carboxykinase Activity

open access: yes, 2019
Phosphoenolpyruvate carboxykinase (PEPCK) is a ubiquitous enzyme found in all known groups of organisms, acting in the reversible conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) in the presence of divalent metal ion, and dependent of ...
Arlene G. CorrĂȘa (7529045)   +4 more
core   +1 more source

Endotoxin causes reciprocal changes in hepatic nitric oxide synthesis, gluconeogenesis, and flux through phosphoenolpyruvate carboxykinase

open access: yes, 1994
Treatment of rats with bacterial endotoxin resulted in a significant induction of hepatic nitric oxide synthase within 3 hours. The response was maximal at 12 hours and was maintained over 18 hours.
Robert A Horton (16068410)   +2 more
core   +1 more source

Human PCK1 Encoding Phosphoenolpyruvate Carboxykinase Is Located on Chromosome 20q13.2

open access: yes, 1993
Cytoplasmic liver phosphoenolpyruvate carboxykinase (GTP)(PEPCK) catalyzes a rate-limiting step in gluconeogenesis. Primers derived from the rat liver PEPCK sequence were used to amplify a portion of the human liver cDNA and to screen a YAC library of ...
Thun, Rachel   +5 more
core   +1 more source

The isolation and functional identification of a phosphoenolpyruvate carboxykinase gene from Saccharina japonica

open access: yesAquaculture and Fisheries
Similar to other macroalgae, Saccharina japonica has CO2-concentrating mechanism (CCM) that allows high photosynthesis efficiency and elevates biomass. Phosphoenolpyruvate carboxykinase (PEPCK) in cytoplasm is an essential component of CCM.
Peichong Lin   +4 more
doaj   +1 more source

Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney

open access: yes, 2003
Aims/hypothesis: To study the secondary consequences of impaired suppression of endogenous glucose production (EGP) we have created a transgenic rat overexpressing the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK) in the kidney. The aim
J Zajac (13293465)   +8 more
core  

Biallelic pathogenic variants in the mitochondrial form of phosphoenolpyruvate carboxykinase cause peripheral neuropathy. [PDF]

open access: yesHGG Adv, 2023
Sondheimer N   +10 more
europepmc   +1 more source

MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5. [PDF]

open access: yesOncogenesis, 2023
Cheung AH   +14 more
europepmc   +1 more source

Rapid changes in the concentration of phosphoenolpyruvate carboxykinase mRNA in rat liver and kidney. Effects of insulin and cyclic AMP

open access: yes, 1982
Starvation and diabetes both caused a marked increase in the concentration of hepatic phosphoenolpyruvate caroboxykinase mRNA while the administration of insulin to diabetic rats or refeeding glucose to starved animals caused a marked reduction in the ...
Cimbala, M. A.   +5 more
core  

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