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Regulation and clinical manifestations of gluconeogenesis dysfunction. [PDF]
Bobok N.
europepmc +1 more source
Phosphoenolpyruvate carboxykinase and gluconeogenesis in grape pericarp
Glycolysis from sugars is necessary at all stages of development of grape pericarp, and this raises the question as to why gluconeogenesis from malate occurs. Phosphoenolpyruvate carboxykinase (PEPCK) is required for gluconeogenesis in grape pericarp.
Walker, Robert P. +5 more
semanticscholar +4 more sources
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Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?
Phosphoenolpyruvate carboxykinase (PEPCK) catalyses the reversible decarboxylation of oxaloacetate to yield phosphoenolpyruvate and CO2. The role of the enzyme in gluconeogenesis and anaplerotic reactions in a range of organisms is discussed, along with ...
R P Walker, R C Leegood, P J Lea
exaly +5 more sources
Inhibition of phosphoenolpyruvate carboxykinase by streptonigrin
Biochemical Pharmacology, 1982Streptonigrin, an antibiotic with antineoplastic activity, inhibited rat liver phosphoenolpyruvate carboxykinase with an I50 of 0.3 microM when excess FeCl2 was present. No inhibition occurred in the absence of added metal ion. Inhibition was partial and noncompetitive versus ITP and oxalacetic acid.
M L, Merryfield, H A, Lardy
openaire +2 more sources
Stereochemistry of phosphoenolpyruvate carboxylation catalyzed by phosphoenolpyruvate carboxykinase
Biochemistry, 1986The stereochemistry of the carboxylation of phosphoenolpyruvate to yield oxalacetate, catalyzed by chicken liver phosphoenolpyruvate carboxykinase and by Ascaris muscle phosphoenolpyruvate carboxykinase, was determined. The substrate (Z)-3-fluorophosphoenolpyruvate was used for the stereochemical analysis.
S H, Hwang, T, Nowak
openaire +2 more sources
A highly specific and sensitive assay for the determination of phosphoenolpyruvate carboxykinase (PEPCK) in nanogram-sized tissue samples is described. This test system is based on the stoichiometric transformation of phosphoenolpyruvate into ATP.
Wimmer M
exaly +2 more sources
Comparative Biochemistry and Physiology Part B Comparative Biochemistry, 2018
Hypoxic zones in marine environments are spreading around the world affecting the survival of many organisms. Marine animals have several strategies to respond to hypoxia, including the regulation of gluconeogenesis.
Carlos A Reyes-Ramos +5 more
semanticscholar +1 more source
Hypoxic zones in marine environments are spreading around the world affecting the survival of many organisms. Marine animals have several strategies to respond to hypoxia, including the regulation of gluconeogenesis.
Carlos A Reyes-Ramos +5 more
semanticscholar +1 more source

