Results 291 to 300 of about 369,030 (389)

Plasmopara viticola Effector PvRXLR10 Targets a Host Phospholipase VvipPLA-IIδ2 to Suppress Plant Immunity in Grapevine. [PDF]

Mol Plant Pathol
Qu J, Liu L, Zheng C, Guo Z, Sun D, Pan F, Lu J, Yin L.   +7 more
europepmc   +1 more source

PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron

Nature Genetics, 2006
N. Morgan, S. Westaway, J. Morton, A. Gregory, P. Gissen, Scott Sonek, H. Cangul, H. Cangul, J. Coryell, N. Canham, N. Nardocci, G. Zorzi, S. Pasha, D. Rodriguez, I. Desguerre, A. Mubaidin, E. Bertini, R. Trembath, A. Simonati, C. Schanen, Colin A. Johnson, B. Levinson, C. Woods, Beth Wilmot, P. Kramer, J. Gitschier, J. Gitschier, E. Maher, S. Hayflick   +28 more
semanticscholar   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Visceral fat lipolysis by pancreatic lipases worsens heart failure. [PDF]

Cell Rep Med
Smichi N, Khatua B, Kostenko S, de Oliveira C, El Kurdi B, Devani KH, Trivedi S, Summers M, McFayden B, Navina S, Patel K, Jahangir S, Belohlavek M, Singh VP.   +13 more
europepmc   +1 more source

Action of Phospholipase A at Interfaces

, 1973
Robert Verger, Maria C.E. Mieras, Gerard H. De Haas   +2 more
openalex   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

When Serum Anti-Phospholipase A2 Receptor Antibodies Go Missing: The Challenge of Predicting Relapse. [PDF]

Kidney Int Rep
Allinovi M, Peyronel F.
europepmc   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes. [PDF]

Mol Microbiol
Lamrabet O, Munoz-Ruiz R, Ayadi I, Bourbon A, Pain E, Oddy J, Cosson P.   +6 more
europepmc   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source