Results 291 to 300 of about 298,796 (340)

High‐permeability cellulose nanocrystals mediate systemic zinc redistribution through nsLTP2‐dependent immune potentiation in plants

Plant Biotechnology Journal, EarlyView.
Summary Zinc (Zn2+) is an essential micronutrient that regulates plant growth, immunity and antiviral defence mechanisms. However, its limited bioavailability often necessitates excessive application, resulting in inefficiencies in production and environmental stress.
Jing Wang, Shunyu Xiang, Xiaoyan Wang, Yang Shen, Changyun Liu, Xin Zhu, Weina Liu, Shanzhi Wang, Xiaozhou Ma, Jin Huang, Xianchao Sun   +10 more
wiley   +1 more source

Prediction of first-in-human dose for new composition bee venom based on allometric scaling and pharmacokinetic modeling approach. [PDF]

Transl Clin Pharmacol
Chae SU, Min JS, Jo SJ, Lee CB, Park J, Bae SH, Bae SK.   +6 more
europepmc   +1 more source

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

Plant, Cell &Environment, EarlyView.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse, Łukasz Paweł Tarkowski, Martial Briand, David Lalanne, Nicolas W. G. Chen, Matthieu Barret, Jerome Verdier   +6 more
wiley   +1 more source

Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from <i>Loxosceles</i> spiders. [PDF]

Toxicon X
Catalán A, García C, Sambra V, Cadena N, Rojas J, Arán-Sekul T, San Francisco J, Vásquez-Saez V, Muñoz C, Vásquez A, Araya JE.   +10 more
europepmc   +1 more source

Classical Juvenile Pityriasis Rubra Pilaris Treated With Secukinumab: Case Report and a Review of Biological Treatments in the Pediatric Population

Pediatric Dermatology, EarlyView.
ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton, Giuseppe Stinco, Enzo Errichetti   +2 more
wiley   +1 more source

The Effects of the Combined Co-Expression of GroEL/ES and Trigger Factor Chaperones on Orthopoxvirus Phospholipase F13 Production in E. coli. [PDF]

BioTech (Basel)
Merkuleva IA, Nikitin VN, Belaya TD, Mustaev EA, Shcherbakov DN.   +4 more
europepmc   +1 more source

The Landscape of Cancer Metabolism as a Therapeutic Target

Pathology International, EarlyView.
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley   +1 more source

Joint association of remnant cholesterol and lipoprotein-associated phospholipase A2 with composite adverse events: A 12-year follow-up study from Asymptomatic Polyvascular Abnormalities Community study. [PDF]

Diabetes Obes Metab
Liu Y, Zhang L, Xu Y, Zhou T, Wu W, Zhang K, Xu R, Chen W, Xu W, Zhou Y, Zheng X, Chen B.   +11 more
europepmc   +1 more source

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

Experimental Physiology, EarlyView.
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto, Anna V. Golubeva, Alvaro Lopez Gallardo, Thomaz F. S. Bastiaanssen, Alexander V. Zhdanov, Gerard M. Moloney, Caitriona Scaife, Jane A. English, Susan A. Joyce, Timothy G. Dinan, John F. Cryan   +10 more
wiley   +1 more source

Dual Role for Pld1 in <i>Klebsiella pneumoniae</i> Virulence: Transcriptomics and Proteomics Provide Insights into Direct and Indirect Effects. [PDF]

J Proteome Res
de Carvalho MML, Nascimento TSD, Rocha GM, Barbosa LC, Bisch PM, Delporte C, van Antwerpen P, Ruysschaert JM, Batista PR, Lery LMS.   +9 more
europepmc   +1 more source