Phenotypic and Molecular Characterization of <i>Candida albicans</i> Isolates from Mexican Women with Vulvovaginitis. [PDF]
Díaz-Huerta H+9 more
europepmc +1 more source
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot+13 more
wiley +1 more source
Genomic Insights into the Phosphatidylinositol-Specific Phospholipase C Gene Family in <i>Leishmania major</i> and <i>Leishmania infantum</i>: Expression Patterns and Potential Association with Drug Resistance. [PDF]
Sirekbasan S, Osman SS, Gürkök-Tan T.
europepmc +1 more source
Regulating the Plasticity of Hippocampal Neurons via Electroacupuncture in Depression Model Mice
This study explores the regulation of the plasticity of hippocampal neurons via electroacupuncture in corticosterone‐induced depression model mice. Electroacupuncture at the Zusanli (ST36) acupoint alleviated depression‐like symptoms and enhanced neuronal plasticity in the hippocampal CA1 region by upregulating BDNF and CaMKIIβ, highlighting its ...
Yiyang Wang+7 more
wiley +1 more source
Assessing the Utility of Broad-Acting Inhibitors as Therapeutics in Diverse Venoms. [PDF]
Kadler R, Morrison B, Yanagihara AA.
europepmc +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
Design, Synthesis, and Testing of 1,2,3-Triazolo-Quinobenzothiazine Hybrids for Cytotoxic and Immunomodulatory Activity. [PDF]
Giercuszkiewicz-Haśnik K+3 more
europepmc +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
AhR Activation at the Air-Blood Barrier Alters Systemic microRNA Release After Inhalation of Particulate Matter Containing Environmentally Persistent Free Radicals. [PDF]
Aryal A+5 more
europepmc +1 more source