Results 191 to 200 of about 28,776 (298)

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

Amiodarone-induced acute liver failure in an infant with paroxysmal supraventricular tachycardia. [PDF]

Ann Pediatr Cardiol
Gupta A, Ravi N, Dhinaharan R, Parihar M, Chakrabarti S, Shrivastava Y, Tiwari LK.   +6 more
europepmc   +1 more source

New Insights into the Bioenergetic and Immunomodulatory Properties of Phospholipases A₂ from <i>Bothrops diporus</i> Venom. [PDF]

Toxins (Basel)
Sasovsky DJ, Oliveira AK, Silva DT, Ojeda GA, Almarza C, Lomonte B, Fox JW, Urra FA, Bustillo S.   +8 more
europepmc   +1 more source

Global identification of Chromobacterium violaceum T6SS effectors reveals an Rhs antibacterial toxin featuring FIX and ADP-ribosyltransferase domains. [PDF]

J Biol Chem
Alves JA, Pankov G, Frey AM, Trost M, Sgro GG, Coulthurst SJ, da Silva Neto JF.   +6 more
europepmc   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Cyclooxygenases in pancreatic ductal adenocarcinoma: are they inflammatory catalysts for tumor growth. [PDF]

Front Oncol
Orhan A, Orhan T, Raskov H, Gögenur I.
europepmc   +1 more source

Serum Lipidomics Profiling Identify Novel Biomarkers of Distal Symmetrical Polyneuropathy in Type 1 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk, Tina Okdahl, Marietta Kokla, Tommi Suvitaival, Gurjeet Kaur, Ismo M. Mattila, Simon M. Kienle, Christian Buhl, Knud Yderstræde, Troels S. Jensen, Peter Rossing, Flemming Pociot, Birgitte Brock, Cristina Legido‐Quigley, Páll Karlsson, Christian S. Hansen, Christina Brock, Joachim Størling, Karolina Sulek   +18 more
wiley   +1 more source

Mucosal immune response modulated by secreted and membrane-bound hydrolases of <i>Candida albicans</i> in vulvovaginal candidiasis. [PDF]

Front Fungal Biol
Qian G, Ding L, Tan C, Wang L, Long C.
europepmc   +1 more source

Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aims Weight loss after metabolic bariatric surgery (MBS) is heterogeneous, and the contribution of liver histology and genetic susceptibility to insufficient weight loss (IWL) or weight regain (WR) remains unclear. We assessed the prevalence of IWL and WR after MBS and their association with liver histology and metabolic ...
Felice Cinque, Marica Meroni, Sara Badiali, Miriam Longo, Erika Paolini, Elisa Galfrascoli, Giovanna Oberti, Giuseppina Pisano, Gabriele Maffi, Matteo Mureddu, Elena Corbetta, Valentina Scimè, Emma Calzavara, Francesca Alletto, Annalisa Cespiati, Luigi Boni, Anna Ludovica Fracanzani, Paola Dongiovanni, Rosa Lombardi   +18 more
wiley   +1 more source

<i>Megalomyrmex milenae</i> Transcriptome Reveals a Complex Venom Cocktail. [PDF]

Toxins (Basel)
Sozanski KS, Coelho GR, Ishihara MA, Delgado A, Adams RMM.   +4 more
europepmc   +1 more source