Results 231 to 240 of about 144,128 (376)

Integrating construction and spatial imaging of organoid for tumor metabolic heterogeneity and interactions

VIEW, EarlyView.
Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo, Zhaohua Xia, Jiaxin Wang, Xiaoling Yu, Chuanyue Wu, Qian Luo, Chao Zhao   +6 more
wiley   +1 more source

Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells. [PDF]

Transl Oncol
Tressler CM, Sonkar K, Cheng M, Ayyappan V, Cai R, Glunde K.   +5 more
europepmc   +1 more source

Influence of phospholipase C on some electrical properties of the skeletal muscle membrane

, 1967
Edson X. Albuquerque, S. Thesleff
openalex   +2 more sources

Enhancement of bee venom phospholipase A₂ activity by melittin, direct lytic factor from cobra venom and polymyxin B [PDF]

, 1974
Christa Mollay, Günther Kreil
openalex   +1 more source

Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity

FASEB BioAdvances, EarlyView.
Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno, Natascia Guida, Mariarosaria Cammarota, Silvia Ruggiero, Angelo Serani, Francesca Galasso, Vincenzo Pizzorusso, Francesca Boscia, Luigi Formisano   +8 more
wiley   +1 more source

Comment on: Nucleotidase as a Clinical Prognostic Marker in Snakebites: A Prospective Study. [PDF]

Indian J Crit Care Med
Mohanty CR, Magoon R, Suresh V, Radhakrishnan RV.   +3 more
europepmc   +1 more source

Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine

FASEB BioAdvances, EarlyView.
Plasmalogens are specialized lipids affecting the membrane structure, dynamics, and key cell signaling pathways. They protect cells from oxidative damage. Plasmalogen deficiency is associated with severe diseases. Lipid nanoparticles and nanomedicine offer unexplored therapeutic potential for restoring plasmalogen levels under pathological conditions ...
Yu Wu, Yuru Deng, Borislav Angelov, Angelina Angelova   +3 more
wiley   +1 more source

Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves. [PDF]

Front Plant Sci
Wei Y, Cai Z, Che Z, Guo X, Ge S, Che X, Deng J, Zhang H, He L, Xu J.   +9 more
europepmc   +1 more source

The action of phospholipase A₂ purified from Crotalus atrox venom on specifically labelled 2‐acyl‐1‐alk‐1‐enyl‐ and 2‐acyl‐1‐al kyl‐sn‐glycero‐3‐phosphorylcholine [PDF]

, 1974
H Woelk, Katsuyo Peiler-Ichikawa
openalex   +1 more source

Phosphatidylethanol in post‐mortem blood: A comparative study of blood matrices and its stability at routine storage conditions

Journal of Forensic Sciences, EarlyView.
Abstract Determination of alcohol markers in post‐mortem cases can be useful to classify drinking habits and potential alcohol habituation prior to death. Phosphatidylethanol (PEth) is a direct alcohol marker and is already commonly used in a variety of contexts.
Jeremai Hose, Hilke Andresen‐Streichert, Mario Thevis, Markus A. Rothschild, Martin Juebner   +4 more
wiley   +1 more source