Results 301 to 310 of about 146,174 (378)

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi   +14 more
wiley   +1 more source

Plasma proteomic profiles of patients during oral anti‐coagulant treatment with vitamin K antagonists

open access: yes
British Journal of Haematology, EarlyView.
Eleonora Camilleri   +8 more
wiley   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck   +1 more
wiley   +1 more source

Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves. [PDF]

open access: yesFront Plant Sci
Wei Y   +9 more
europepmc   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto   +12 more
wiley   +1 more source

Molecular mechanisms of CBASS phospholipase effector CapV mediated membrane disruption. [PDF]

open access: yesNat Commun
Kong J   +23 more
europepmc   +1 more source

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