Implication of Glycerol and Phospholipid Transporters in Mycoplasma pneumoniae Growth and Virulence [PDF]
Stephanie Großhennig +4 more
openalex +1 more source
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
Identification of diagnostic and prognostic phospholipid biomarkers in idiopathic pulmonary fibrosis via machine learning and in vivo validation. [PDF]
Yang L +6 more
europepmc +1 more source
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
Cryo-EM structure of the ATP11C Q79E mutant reveals the structural basis for altered Phospholipid recognition. [PDF]
Qian Y +5 more
europepmc +1 more source
Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution
Partial Replacement of phospholipid lipid by cationic lipid improves storage stability of commercial mRNA LNPs by stabilizing their internal microstructure. Abstract Messenger RNA lipid nanoparticles (mRNA‐LNPs) have achieved remarkable success in clinical vaccination efforts to curb the COVID‐19 pandemic, and have attracted tremendous interest from ...
Rui Chen +8 more
wiley +1 more source
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang +6 more
wiley +1 more source
Compositional selection of phospholipid compartments in icy environments drives the enrichment of encapsulated genetic information. [PDF]
Shinoda T +5 more
europepmc +1 more source
A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products [PDF]
Kimberly A. Walton +6 more
openalex +1 more source

