Results 181 to 190 of about 300,277 (292)

Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets [PDF]

open access: hybrid, 2014
Lei Liu   +10 more
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Snake Venom PLA<sub>2</sub> as Anticoagulant Agents: Role of Crotoxin, from <i>Crotalus durissus</i> Rattlesnake, in Hemostasis. [PDF]

open access: yesToxins (Basel)
Brasileiro-Martins LM   +11 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

Cellular Responses to Excess Phospholipid [PDF]

open access: hybrid, 1999
Irina Baburina, Suzanne Jackowski
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

open access: yesAdvanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong   +15 more
wiley   +1 more source

Advances in Lycopene Production: From Natural Sources to Microbial Synthesis Using <i>Yarrowia lipolytica</i>. [PDF]

open access: yesMolecules
Moroz P   +7 more
europepmc   +1 more source

High Plasma Phospholipid Transfer Protein Levels as a Risk Factor for Coronary Artery Disease [PDF]

open access: bronze, 2003
Axel Schlitt   +6 more
openalex   +1 more source

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