A review on phospholipids and their main applications in drug delivery systems
Phospholipids have the characteristics of excellent biocompatibility and a especial amphiphilicity. These unique properties make phospholipids most appropriate to be employed as important pharmaceutical excipients and they have a very wide range of ...
Yihui Deng
exaly +4 more sources
General model of phospholipid bilayers in fluid phase within the single chain mean field theory [PDF]
Coarse-grained model for saturated (DCPC, DLPC, DMPC, DPPC, DSPC) and unsaturated (POPC, DOPC) phospholipids is introduced within the Single Chain Mean Field theory. A single set of parameters adjusted for DMPC bilayers gives an adequate description of equilibrium and mechanical properties of a range of saturated lipid molecules that differ only in ...
Baulin, Vladimir A.+2 more
arxiv +3 more sources
Thermodynamic Approach to Phase Coexistence in Ternary Phospholipi-Cholesterol Mixtures [PDF]
We introduce a simple and predictive model for determining the phase stability of ternary phospholipid-cholesterol mixtures. Assuming that competition between the liquid and gel order of the phospholipids is the main driving force behind lipid segregation, we derive a Gibbs free-energy of mixing, based on the thermodynamic properties of the lipids main
Marques, Carlos M.+2 more
arxiv +5 more sources
While the beneficial roles of dietary phospholipids on health status and overall performances of fish larvae have been well demonstrated, the underlying mechanisms remain unclear.
Shilin Wang+8 more
doaj +1 more source
Phospholipids (PLs) are amphiphilic molecules that are in charge of controlling what goes in or out of the cell, keeping up the structure and numerous associated functions.
Manikandan Alagumuthu+2 more
doaj +1 more source
Value of Ascitic Lipids in the Differentiation between Cirrhotic and Malignant Ascites [PDF]
Ascitic fluid concentrations of cholesterol, triglycerides and phospholipids, were compared with ascitic fluid total protein in 40 patients with chronic liver disease, 51patients with various neoplasms and 1 patient with cardiac failure.
Alexander L. Gerbes+22 more
core +1 more source
Detailed study of Brazil nut (Bertholletia excelsa) oil micro-compounds : Phospholipids, tocopherols and sterols [PDF]
The oil of the Brazil nut (Bertholletia excelsa) was studied for its composition in fatty acids, tocopherols, sterols and phospholipids. The fatty acids composition of phospholipids was also studied.
Brochier, José+4 more
core +1 more source
Influence of pretreatments for extraction of lipids from yeast by using supercritical carbon dioxide and ethanol as cosolvent [PDF]
Saccharomyces cerevisiae is one of the most studied and industrially exploited yeast. It is a non-oleaginous yeast whose lipids are mainly phospholipids.
Camy, Séverine+3 more
core +1 more source
Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? [PDF]
The regulation of ion channels by anionic phospholipids is currently very topical. An outstanding issue is whether phosphatidylinositol 4,5-diphosphate and related species act as true second messengers in signaling or behave in a manner analogous to an ...
Clapp, LH+4 more
core +1 more source
Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell+59 more
core +1 more source