Results 141 to 150 of about 53,922 (240)

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

Lipid metabolism in fatty liver of lysine- and threonine-deficient rats

open access: yesJournal of Lipid Research, 1966
Rats were fed a low protein diet deficient in and supplemented with lysine and threonine. Liver lipids contained more lecithin, sphingomyelin, and free fatty acids, and less amino phospholipids in the deficient rats.
R. Viviani, A.M. Sechi, G. Lenaz
doaj  

THE DETERMINATION OF CHOLINE IN PHOSPHOLIPIDS

open access: hybrid, 1944
C. Entenman, Alvin Taurog, I.L. Chaikoff
openalex   +1 more source

Biomimetic MOF Nanocarrier‐Mediated Synergistic Delivery of Mitochondria and Anti‐Inflammatory miRNA to Alleviate Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
A biomimetic MOF nanocarrier for macrophage‐targeting delivery of both mitochondria and anti‐miR‐127 is designed with an aim to revitalize macrophages and remold the inflammatory microenvironment for treating acute lung injury. By leveraging the macrophages‐targeting property and pH‐responsiveness, ZIF‐8 nanocarriers facilitated efficient delivery of ...
Xin Shou   +10 more
wiley   +1 more source

Global changes in phospholipids identified by MALDI MS in rats with focal cerebral ischemia[S]

open access: yesJournal of Lipid Research, 2012
Neuronal membrane phospholipids are highly affected by oxidative stress caused by ischemic injury. Thus, it is necessary to identify key lipid components that show changes during ischemia to develop an effective approach to prevent brain damage from ...
Selina Rahman Shanta   +6 more
doaj  

PHOSPHOLIPID CONTENT AND ACTIVITY IN MUSCLE

open access: hybrid, 1934
W.R. Bloor, Ruth H. Snider
openalex   +1 more source

Phospholipid precursors of prostaglandins [PDF]

open access: green, 1968
William E.M. Lands, Bengt Samuelsson
openalex   +1 more source

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

open access: yesAdvanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing   +4 more
wiley   +1 more source

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