Results 161 to 170 of about 368,892 (358)

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

The incorporation of dimethylaminoethanol and dimethylaminoisopropyl alcohol into Phormia regina phospholipids*

open access: yesJournal of Lipid Research, 1963
The effect of replacing dietary choline with dimethylaminoethanol and dimethylaminoisopropyl alcohol on the larval phospholipids of the blowfly Phormia regina was investigated. It was found that these compounds were incorporated into the phospholipids to
Loran L. Bieber, R.W. Newburgh
doaj  

THE DETERMINATION OF CHOLINE IN PHOSPHOLIPIDS

open access: hybrid, 1944
C. Entenman, Alvin Taurog, I.L. Chaikoff
openalex   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren   +11 more
wiley   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria. [PDF]

open access: yes, 1989
Bandlow W.   +43 more
core   +3 more sources

Phospholipids and Related Substances as Growth Substrates for Soil Microorganisms1 [PDF]

open access: gold, 1956
Albert Schatz   +2 more
openalex   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang   +9 more
wiley   +1 more source

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