Results 161 to 170 of about 53,922 (240)

Lipid Droplets Metabolism Mediated by ANXA7‐PPARγ Signaling Axis Regulates Spinal Cord Injury Repair in Mice

open access: yesAdvanced Science, EarlyView.
This work proposes a new mechanism for the regulation of LDs metabolism by ANXA7/PPARγ. ANXA7 can interact with PPARγ to promote its stability. ANXA7 activation promotes PPARγ nuclear translocation, thus promoting LDs formation and interaction with mitochondria by promoting PLIN5 expression.
Lu Chen   +6 more
wiley   +1 more source

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

open access: yesAdvanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu   +12 more
wiley   +1 more source

THE METABOLISM OF THE PHOSPHOLIPIDS

open access: hybrid, 1930
Robert Gordon Sinclair
openalex   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

open access: yesAdvanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang   +4 more
wiley   +1 more source

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

open access: yesAdvanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong   +5 more
wiley   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

open access: yesCancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin   +6 more
wiley   +1 more source

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