Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao +10 more
wiley +1 more source
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu +7 more
wiley +1 more source
Incorporation of Hydroxyeicosatetraenoic Acid Isomers into Macrophage Phospholipids Reveals Class-Specific Distribution. [PDF]
Garrido A +4 more
europepmc +1 more source
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Flaxseed feeding enriches plasmalogens and glycosphingolipids and alters the esterification site of PUFAs in egg yolk phospholipids based on lipidomics analysis. [PDF]
Wang Y +6 more
europepmc +1 more source
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang +9 more
wiley +1 more source
Salivary cortisol dynamics and their relationship with sleep and mental well-being in adults receiving a phospholipid-based <i>Melissa officinalis</i> supplement: a secondary analysis in a subpopulation. [PDF]
Mazzola G +5 more
europepmc +1 more source
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen +8 more
wiley +1 more source
Meta-Analysis of Bioaccessibility of Hydrophobic Compounds in Buttermilk Matrices: A Systematic Review and Quantitative Synthesis. [PDF]
Sagandyk A +6 more
europepmc +1 more source
The Adsorption of Phospholipids at the Interface
The adsorption of phospholipids on different types of substrate was studied. The adsorbate-surface interactions play an important role in the formation of supported phospholipid bilayer. The deposition of phospholipids on atomically flat surfaces as mica,
Sokolová, Romana
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