Results 11 to 20 of about 519,923 (401)

A review on phospholipids and their main applications in drug delivery systems

open access: yesAsian Journal of Pharmaceutical Sciences, 2015
Phospholipids have the characteristics of excellent biocompatibility and a especial amphiphilicity. These unique properties make phospholipids most appropriate to be employed as important pharmaceutical excipients and they have a very wide range of ...
Yihui Deng
exaly   +4 more sources

Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing

open access: yesNature Materials, 2021
Endosomal escape remains a fundamental barrier hindering the advancement of nucleic acid therapeutics. Taking inspiration from natural phospholipids that comprise biological membranes, we report the combinatorial synthesis of multi-tailed ionizable ...
Daniel J Siegwart   +2 more
exaly   +2 more sources

Efficiency evaluation of phospholipid fatty acid method based on lipid standards: methanol failed to recover a majority of phospholipids yet eluted unexpected glycolipid [PDF]

open access: yesFrontiers in Microbiology
Phospholipid fatty acid (PLFA) method has been popular and powerful for characterizing soil microbial communities over decades. However, little is known about efficiencies of acidic vs.
Shanshan Zhang   +5 more
doaj   +2 more sources

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage

open access: yeseLife, 2018
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated.
Marco M Manni   +5 more
doaj   +2 more sources

Phospholipids of Animal and Marine Origin: Structure, Function, and Anti-Inflammatory Properties

open access: yesMolecules, 2017
In this review paper, the latest literature on the functional properties of phospholipids in relation to inflammation and inflammation-related disorders has been critically appraised and evaluated.
Ronan Lordan   +2 more
doaj   +2 more sources

The use of natural and synthetic phospholipids as pharmaceutical excipients

open access: yesEuropean Journal of Lipid Science and Technology, 2014
In pharmaceutical formulations, phospholipids obtained from plant or animal sources and synthetic phospholipids are used. Natural phospholipids are purified from, e.g., soybeans or egg yolk using non-toxic solvent extraction and chromatographic ...
P. van Hoogevest, A. Wendel
exaly   +2 more sources

The oily nucleus– role of phospholipids in genome biology: membrane-directed roles and signaling in the nucleoplasm [PDF]

open access: yesCellular and Molecular Life Sciences
Phospholipids, widely known for their structural role in cellular membranes, are now also recognized to play pivotal roles in signal transduction, metabolism, and cellular homeostasis.
Zobia Umair   +3 more
doaj   +2 more sources

The inositol phospholipids [PDF]

open access: yesJournal of Lipid Research, 1960
T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
J.N. Hawthorne
doaj   +3 more sources

Phospholipids of the Thiobacilli [PDF]

open access: bronzeJournal of Bacteriology, 1968
Phosphatidyl glycerol, disphosphatidyl glycerol, and phosphatidyl ethanolamine were found in all of the Thiobacillus species studied. T. thioparus possessed only these phospholipids. T. intermedius, T. neapolitanus , and T. thiooxidans contained
Judith K. Barridge, Jessup Shively
openalex   +4 more sources

The metabolism and function of phospholipids in Mitochondria

open access: yesMitochondrial Communications, 2023
Mitochondria are important organelles of eukaryotic cells and involved in a variety of cellular processes including oxidative phosphorylation for generating ATP, apoptosis, steroid synthesis, and signal transduction.
Jun Dong   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy