A review on phospholipids and their main applications in drug delivery systems
Asian Journal of Pharmaceutical Sciences, 2015 Phospholipids have the characteristics of excellent biocompatibility and a especial amphiphilicity. These unique properties make phospholipids most appropriate to be employed as important pharmaceutical excipients and they have a very wide range of ...
Jing Li +6 more
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Phospholipids of Animal and Marine Origin: Structure, Function, and Anti-Inflammatory Properties
Molecules, 2017 In this review paper, the latest literature on the functional properties of phospholipids in relation to inflammation and inflammation-related disorders has been critically appraised and evaluated.
Ronan Lordan +2 more
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eLife, 2018 Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated.
Marco M Manni +5 more
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Nature Materials, 2021 Endosomal escape remains a fundamental barrier hindering the advancement of nucleic acid therapeutics. Taking inspiration from natural phospholipids that comprise biological membranes, we report the combinatorial synthesis of multi-tailed ionizable ...
Shuai Liu +6 more
semanticscholar +1 more source
The Phospholipid Research Center: Current Research in Phospholipids and Their Use in Drug Delivery
Pharmaceutics, 2020 This review summarizes the research on phospholipids and their use for drug delivery related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that have been approved by the PRC since 2017 and are currently still ongoing or ...
Simon Drescher, P. van Hoogevest
semanticscholar +1 more source
Oxidized Phospholipids are Proinflammatory and Proatherogenic in Hypercholesterolemic Mice
Nature, 2018 Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues, including atherosclerotic lesions, and frequently mediate proinflammatory changes1.
X. Que +21 more
semanticscholar +1 more source
The phospholipids of corynebacteria [PDF]
Lipids, 1971 AbstractThe phospholipids ofCorynebacterium diphtheriae, Corynebacterium xerosis, Corynebacterium equi andCorynebacterium ovis were examined, largely by chromatographic procedures. In all of these, lipids of the phosphoinositide and mannophosphoinositide type were prominent.
Brennan, Patrick J., Lehane, Derek P.
openaire +3 more sources
Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication [PDF]
, 2010 Background Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the
Castorena, Kathryn M +2 more
core +4 more sources
Understanding phosphoinositides: rare, dynamic, and essential membrane phospholipids.
Biochemical Journal, 2019 Polyphosphoinositides (PPIs) are essential phospholipids located in the cytoplasmic leaflet of eukaryotic cell membranes. Despite contributing only a small fraction to the bulk of cellular phospholipids, they make remarkable contributions to practically ...
E. Dickson, B. Hille
semanticscholar +1 more source
Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
STAR Protocols, 2023 Summary: Ubiquitin is covalently conjugated to phospholipids as well as proteins; however, ubiquitinated phospholipids are less abundant than free ubiquitin and ubiquitinated proteins.
Jun-ichi Sakamaki, Noboru Mizushima
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