Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
Fingolimod as a potent anti-Staphylococcus aureus: pH-dependent cell envelope damage and eradication of biofilms/persisters. [PDF]
Shang Y+5 more
europepmc +1 more source
Molecular Mechanisms of Pathogenic Fungal Virulence Regulation by Cell Membrane Phospholipids. [PDF]
Li Y+5 more
europepmc +1 more source
Reduced Triphosphopyridine Nucleotide Oxidase-catalyzed Alterations of Membrane Phospholipids
H E May, Paul B. McCay
openalex +1 more source
The calcium-stimulated incorporation of ethanolamine and serine into the phospholipids of the housefly Musca domestica [PDF]
H.D. Crone
openalex +1 more source
Carbon nanosol (CNS) exhibits rapid root penetration capacity, enhancing plant growth through boosting stomatal density and antioxidative enzyme activity. Single‐cell transcriptomic profiling uncovers cell type‐specific gene expression patterns and developmental trajectories during CNS‐mediated growth promotion.
Lingtong Cheng+10 more
wiley +1 more source
Non-Targeted Lipidomics Analysis of Characteristic Milk Using High-Resolution Mass Spectrometry (UHPLC-HRMS). [PDF]
Wei T, Zhou T, Zhang S, Quan Z, Liu Y.
europepmc +1 more source
Phospholipid Metabolism in T4 Bacteriophage-infected Escherichia coli K-12 (λ) [PDF]
R H Peterson, C. S. Buller
openalex +1 more source
KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion
Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li+12 more
wiley +1 more source
Impact of blood centrifugation on the parameters of thrombin generation assay revisited to look for possible revision of the current guidance. [PDF]
Scalambrino E+3 more
europepmc +1 more source