Results 251 to 260 of about 523,879 (387)

APOL2 Stabilizes Ku80 to Confer NHEJ‐Mediated Radioresistance in Gastric Cancer

Advanced Science, EarlyView.
Radiotherapy resistance in gastric cancer (GC) is often mediated by enhanced DNA repair. APOL2 is found to promote NHEJ by stabilizing Ku80, conferring radioresistance. High APOL2 correlates with poor prognosis. Formononetin disrupts APOL2‐Ku80, restoring radiosensitivity, suggesting a novel therapeutic strategy.
Dan Zu, Qimei Bao, Hanyi He, Yuke Zhong, Mingcong Deng, Yangchan Hu, Chunkai Zhang, Chen Liang, Yixing Huang, Haidong Liu, Xiao Li, Yanhua He, Guoyan Luo, Weixin Wu, Fenghui Guan, Shengfeng Xu, Min Liu, Albino Bacolla, Ji Jing, Yian Du, John A. Tainer, Yin Shi, Zu Ye, Xiangdong Cheng   +23 more
wiley   +1 more source

Apparent Turnover of Mitochondrial Deoxyribonucleic Acid and Mitochondrial Phospholipids in the Tissues of the Rat

, 1969
Nicholas J. Gross, Godfrey S. Getz, Murray Rabinowitz   +2 more
openalex   +1 more source

Plasma phospholipids and their fatty acid composition in multiple sclerosis [PDF]

, 1966
A. Montfoort, R. W. R. Baker, Robert Thompson, K J Zilkha   +3 more
openalex   +1 more source

Mechanisms of Self-Assembly of Giant Unilamellar Vesicles in the Army Liposome Formulation (ALF) Family of Vaccine Adjuvants. [PDF]

Pharmaceutics
Nicolescu C, Komla E, Rao M, Matyas GR, Alving CR.   +4 more
europepmc   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo, Jiayun Liu, Yunxin Su, Tao Jiang, Xincan Wu, Peng Gao, Tao Qin, Mengyuan Wu, Qingqing Li, Shujun Zhang, Baorong He, Yongxiang Wang, Xiaodong Guo, Wei Zhou, Shujie Zhao, Jin Fan, Jian Chen, Guoyong Yin   +17 more
wiley   +1 more source

The structural characteristics of cellular phospholipid acyl chains required for ABCA1-mediated HDL formation. [PDF]

J Biol Chem
Nagao K, Matsuo M, Hori Y, Namba N, Saito H.   +4 more
europepmc   +1 more source

A Herbal‐Piezoelectric Heterojunction Strategy to Potentiate Bacterial Cuproptosis‐Like Death and Remodel the Inflammatory Microenvironment in Infection‐Associated Implant Osteomyelitis

Advanced Science, EarlyView.
A titanium implant coating integrating berberine and copper‐doped strontium titanate leverages ultrasound to compromise bacterial membranes and induce cuproptosis‐like death. This approach resolves S. aureus infections in osteomyelitis models while suppressing inflammation and promoting osseointegration, demonstrating a dual‐functional strategy against
Guannan Zhang, Zehao Li, Ying Lu, Jianbo Song, Xingyu Liang, Peide Han, Xiaohong Yao, Yongqiang Yang, Xiangyu Zhang   +8 more
wiley   +1 more source

Effect of 7-dehydrocholesterol and cholesterol-loaded cyclodextrins on bull sperm motility during short term storage. [PDF]

, 2017
Daskin, A., Inanc, Me, Olgac, Kt, Ozen, D, Stelletta, Calogero, Tekin, K, Uysal, O   +6 more
core   +1 more source

Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

Advanced Science, EarlyView.
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan, Rongjiao Xi, Yong Kang, Ming‐jie Kuang, Xiaoyuan Ji   +4 more
wiley   +1 more source

Tetraphenylborate stimulation of phospholipid labeling in goldfish brain [PDF]

, 1969
J. E. Den Hollander, John M. Hallenbeck, Bernard W. Agranoff   +2 more
openalex   +1 more source