Results 101 to 110 of about 4,129 (176)
, 2005 GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol +6 more
core
Genomic analysis of 48 paenibacillus larvae bacteriophages [PDF]
, 2018 Indexación: Scopus.Funding: Research at UNLV was funded by National Institute of General Medical Sciences grant GM103440 (NV INBRE), the UNLV School of Life Sciences, and the UNLV College of Sciences. E.C.-N.
Castro-Nallar, E. +7 more
core +1 more source
Exploration, Volume 5, Issue 5, October 2025.In this study, Zhang and colleagues show that drinking‐water supplementation of D‐mannose serves as an effective and potential therapeutic of type 2 diabetes, with improvement of both liver health and bone mass. The effect is exerted through suppressing macrophage release of extracellular vesicles based on metabolic control of CD36 expression.
Sha Zhang +21 more
wiley +1 more source
Journal of the Neurological Sciences, 2017 Fil: Rossi, Malco Damian. Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia; Argentina.
Malco Rossi +3 more
openaire +2 more sources
Disease Models & Mechanisms, 2019 Phosphomannomutase 2 deficiency, or PMM2-CDG, is the most common congenital disorder of glycosylation and affects over 1000 patients globally. There are no approved drugs that treat the symptoms or root cause of PMM2-CDG.
Sangeetha Iyer +10 more
doaj +1 more source
MicrobiologyOpen, Volume 14, Issue 5, October 2025.Klebsiella pneumoniae isolate KPNW showed resistance to all clinically relevant antibiotics. Upon whole genome sequencing and characterization, we detected a large number of antimicrobial resistance genes, resistance‐associated point mutations, virulence determinants, heavy metal resistance genes, and mobile genetic elements in errorits genome ...
Md. Wahid Murad +3 more
wiley +1 more source
Journal of Cellular Biochemistry, Volume 126, Issue 8, August 2025.ABSTRACT Leishmaniasis is a neglected tropical disease with a significant global health burden, particularly in developing countries, where it accounts for approximately 1.6 million new infections annually. Current therapeutic options are limited by severe adverse effects, toxicity, and drug resistance, highlighting the urgent need for novel treatment ...
Eduarda Moreira Barreto +8 more
wiley +1 more source
Additional file 1 of Dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG)
, 2020 Additional file 1: Figure S1. Layout showing the metabolic fate of mannose in mammalian cells. PMM2 is an essential enzyme catalyzing the conversion of mannose-6-phosphate to mannose-1- phosphate, which is the first step in the synthesis. Figure S2.
Taday, Roman +4 more
openaire +1 more source
Clinical Genetics, 2019 The congenital disorders of glycosylation (CDG) are defects in glycoprotein and glycolipid glycan synthesis and attachment. They affect multiple organ/systems, but non‐specific symptoms render the diagnosis of the different CDG very challenging.
Celia Medrano +29 more
openaire +6 more sources
Whole cell biosynthesis of a functional oligosaccharide, 2′-fucosyllactose, using engineered Escherichia coli [PDF]
, 2012 BACKGROUND: 2'-Fucosyllactose (2-FL) is a functional oligosaccharide present in human milk which protects against the infection of enteric pathogens.
Jin-Ho Seo +7 more
core +1 more source