Results 21 to 30 of about 2,733 (110)

Gut Luminal Exosomes in Young and Old Mice: Multi‐Omic Characteristics and Regulation of Gut Permeability

Aging Cell, Volume 25, Issue 4, April 2026.
This graphical abstract shows that gut luminal exosomes (LFEs) change with aging, with old mice producing LFEs that disrupt gut barrier integrity, alter microbiome composition, and promote insulin resistance. In contrast, LFEs from young mice improve gut barrier function and metabolic health, and transferring these LFEs can partially reverse age ...
Abdelnaby Khalyfa, Lyu Zhen, Trupti Joshi, David Gozal   +3 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Characterization and Comparison of Milk Fat Globule Membrane Proteins, Whey Protein Concentrate, and Micellar Casein Concentrate

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This study compared milk fat globule membrane protein (MFGMP) with whey protein concentrate (WPC) and micellar casein concentrate (MCC). The results revealed MFGMP's superior structural stability and amino acid profile, identified its unique proteomic landscape through label‐free quantification, and demonstrated its enhanced in vitro digestibility ...
Jiaming Wang, Xiaoguo Ji, Zhongbo Bian, Yuwei Liu, Wenliang Chen, Chuang Fan, Juan Li   +6 more
wiley   +1 more source

The relationship between neuron-specific enolase and prognosis of patients with acute traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To investigate the relationship between neuron-specific enolase (NSE) levels in serum and cerebrospinal fluid (CSF) of patients with acute traumatic brain injury (TBI) and the prognosis of TBI patients.
Yun-yang LIU, Jing-jian MA, Jin LI, Rui-chao JIA   +3 more
doaj  

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani, William Poulos, Maryam Rahimzadeh Dashtaki, Seyed Amirhossein Sadeghi, Jose B. Cibelli, Fei Fang, Liangliang Sun   +6 more
wiley   +1 more source

Research of the serum level of neuron⁃specific enolase in children with various types of seizure

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To explore the relevance between the level changes of serum neuron⁃specific enolase (NSE) and neuronal damage in various seizure types of children with epilepsy.
Chun WANG, Qiong⁃xiang ZHAI, Zhi⁃hong TANG, Mu⁃qing ZHUO   +3 more
doaj  

Analysis of influencing factors of acute kidney injury after spontaneous intracerebral hemorrhage surgery

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To analyze the influencing factors of acute kidney injury (AKI) after surgery in spontaneous intracranial hemorrhage (sICH). Methods A total of 151 patients with sICH who underwent surgery in Tianjin Huanhu Hospital from March 2023 to June ...
ZHANG Lei, QU Tong-jun, WU Sheng, ZHANG Tao, ZHANG Guo-bin   +4 more
doaj   +1 more source

Comprehensive Pan‐Cancer Analysis of TRNT1 as a Potential Biomarker for Breast Cancer

Journal of Cellular and Molecular Medicine, Volume 29, Issue 18, September 2025.
ABSTRACT TRNT1, an RNA nucleotide transferase, plays a critical role in cellular processes and may be involved in cancer. However, its role in cancer has not been fully explored. This study aims to explore the potential significance of TRNT1 in cancer, particularly in breast cancer (BC) progression and prognosis.
Xinwei Li, Yue Meng, Bing Gu
wiley   +1 more source

Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post‐mortem

Journal of the Science of Food and Agriculture, Volume 105, Issue 10, Page 5163-5172, 15 August 2025.
Abstract Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle.
Nima Hematyar, Tomas Policar, Turid Rustad   +2 more
wiley   +1 more source

Extensive lateral gene transfer between proto‐eukaryotes and Heimdallarchaeia suggests their close association during eukaryogenesis

mLife, Volume 4, Issue 4, Page 345-362, August 2025.
Abstract It has been proposed by Ettema and colleagues, in the two‐domain framework for the tree of life, that Eukarya emerged from Heimdallarchaeia, as sister group to Hodarchaeales. Looking at the individual trees of the protein markers used by these authors, I notice that Eukarya are only sister to Hodarchaeales or other Heimdallarchaeia in a ...
Patrick Forterre
wiley   +1 more source