Results 181 to 186 of about 43,490 (186)

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.

Pharmacology and Therapeutics, 2015
D. Sampath, T. Zabka, D. Misner, T. O'Brien, P. Dragovich   +4 more
semanticscholar   +1 more source

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

Journal of Medicinal Chemistry, 2017
C. Travelli, S. Aprile, R. Rahimian, A. A. Grolla, Federica Rogati, Mattia Bertolotti, F. Malagnino, R. Di Paola, D. Impellizzeri, R. Fusco, Valentina Mercalli, A. Massarotti, G. Stortini, S. Terrazzino, E. Del Grosso, Gohar Fakhfouri, M. Troiani, M. Alisi, G. Grosa, G. Sorba, P. Canonico, G. Orsomando, S. Cuzzocrea, A. Genazzani, U. Galli, G. Tron   +25 more
semanticscholar   +1 more source

Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities

Expert Review of Anticancer Therapy, 2016
Hang Chen, Shiyu Wang, Haiyuan Zhang, E. Nice, Canhua Huang   +4 more
semanticscholar   +1 more source

Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase.

Journal of Medicinal Chemistry, 2017
P. Spacek, D. Keough, M. Chavchich, M. Dračínský, Z. Janeba, L. Naesens, M. Edstein, L. Guddat, D. Hocková   +8 more
semanticscholar   +1 more source

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma

Pigment Cell & Melanoma Research, 2015
A. A. Grolla, S. Torretta, Ilaria Gnemmi, A. Amoruso, G. Orsomando, Marco Gatti, A. Caldarelli, D. Lim, L. Penengo, S. Brunelleschi, A. Genazzani, C. Travelli   +11 more
semanticscholar   +1 more source

First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.

Journal of Medicinal Chemistry, 2015
W. Eng, D. Hocková, P. Spacek, Z. Janeba, N. West, Kyra Woods, L. Naesens, D. Keough, L. Guddat   +8 more
semanticscholar   +1 more source